ID   DF199_ARATH             Reviewed;          84 AA.
AC   Q2V4G5;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Defensin-like protein 199;
DE   Flags: Precursor;
GN   OrderedLocusNames=At1g56553; ORFNames=F25P12;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA   Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT   "Simultaneous high-throughput recombinational cloning of open reading
RT   frames in closed and open configurations.";
RL   Plant Biotechnol. J. 4:317-324(2006).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17565583; DOI=10.1111/j.1365-313x.2007.03136.x;
RA   Silverstein K.A.T., Moskal W.A. Jr., Wu H.C., Underwood B.A., Graham M.A.,
RA   Town C.D., VandenBosch K.A.;
RT   "Small cysteine-rich peptides resembling antimicrobial peptides have been
RT   under-predicted in plants.";
RL   Plant J. 51:262-280(2007).
RN   [5]
RP   GENE FAMILY.
RX   PubMed=15955924; DOI=10.1104/pp.105.060079;
RA   Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT   "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL   Plant Physiol. 138:600-610(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
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DR   EMBL; AC009323; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002684; AEE33407.1; -; Genomic_DNA.
DR   EMBL; DQ912208; ABI34016.1; -; mRNA.
DR   EMBL; EF182772; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; NP_001031200.1; NM_001036123.3.
DR   AlphaFoldDB; Q2V4G5; -.
DR   PaxDb; Q2V4G5; -.
DR   PRIDE; Q2V4G5; -.
DR   ProteomicsDB; 224083; -.
DR   EnsemblPlants; AT1G56553.1; AT1G56553.1; AT1G56553.
DR   GeneID; 3767470; -.
DR   Gramene; AT1G56553.1; AT1G56553.1; AT1G56553.
DR   KEGG; ath:AT1G56553; -.
DR   Araport; AT1G56553; -.
DR   TAIR; locus:1009023092; AT1G56553.
DR   HOGENOM; CLU_183259_0_0_1; -.
DR   OMA; MAITMRT; -.
DR   OrthoDB; 1629889at2759; -.
DR   PhylomeDB; Q2V4G5; -.
DR   PRO; PR:Q2V4G5; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q2V4G5; baseline and differential.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..84
FT                   /note="Defensin-like protein 199"
FT                   /id="PRO_0000379691"
FT   DISULFID        40..80
FT                   /evidence="ECO:0000250"
FT   DISULFID        47..72
FT                   /evidence="ECO:0000250"
FT   DISULFID        56..78
FT                   /evidence="ECO:0000250"
FT   DISULFID        60..79
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   84 AA;  9351 MW;  4E38930CBA1C9CA3 CRC64;
     MAITMRTLVA FVFTIFFIIS FVHSRTTTSG YGMLFDSVAC EGGFEYCPRG GGNDKCTTFC
     RSLPNKYDFG VCDKIYACCC HINV