DF200_ARATH
ID DF200_ARATH Reviewed; 129 AA.
AC A8MRC8; Q8LGD8;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 04-DEC-2007, sequence version 1.
DT 03-AUG-2022, entry version 55.
DE RecName: Full=Defensin-like protein 200;
DE Flags: Precursor;
GN OrderedLocusNames=At5g59105; ORFNames=K18B18.13, MNC17.23;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10048488; DOI=10.1093/dnares/5.6.379;
RA Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence
RT features of the regions of 1,081,958 bp covered by seventeen physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:379-391(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RX PubMed=15955924; DOI=10.1104/pp.105.060079;
RA Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL Plant Physiol. 138:600-610(2005).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC -!- CAUTION: Contains 8 disulfide bonds instead of the 4 disulfide bonds,
CC which are conserved features of the family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM67273.1; Type=Erroneous translation; Note=Wrong choice of frame.; Evidence={ECO:0000305};
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DR EMBL; AB016890; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AB024027; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED97143.1; -; Genomic_DNA.
DR EMBL; AY084327; AAM67273.1; ALT_SEQ; mRNA.
DR RefSeq; NP_680455.2; NM_148150.2.
DR AlphaFoldDB; A8MRC8; -.
DR BioGRID; 21272; 1.
DR STRING; 3702.AT5G59105.1; -.
DR PaxDb; A8MRC8; -.
DR PRIDE; A8MRC8; -.
DR EnsemblPlants; AT5G59105.1; AT5G59105.1; AT5G59105.
DR GeneID; 836028; -.
DR Gramene; AT5G59105.1; AT5G59105.1; AT5G59105.
DR KEGG; ath:AT5G59105; -.
DR Araport; AT5G59105; -.
DR TAIR; locus:504954899; AT5G59105.
DR HOGENOM; CLU_1951738_0_0_1; -.
DR OMA; EGCWCCP; -.
DR OrthoDB; 12226at2759; -.
DR PhylomeDB; A8MRC8; -.
DR PRO; PR:A8MRC8; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; A8MRC8; baseline and differential.
DR Genevisible; A8MRC8; AT.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE 2: Evidence at transcript level;
KW Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..129
FT /note="Defensin-like protein 200"
FT /id="PRO_0000379692"
FT DISULFID 40..78
FT /evidence="ECO:0000250"
FT DISULFID 48..70
FT /evidence="ECO:0000250"
FT DISULFID 56..75
FT /evidence="ECO:0000250"
FT DISULFID 60..77
FT /evidence="ECO:0000250"
FT DISULFID 87..125
FT /evidence="ECO:0000250"
FT DISULFID 95..117
FT /evidence="ECO:0000250"
FT DISULFID 103..122
FT /evidence="ECO:0000250"
FT DISULFID 107..124
FT /evidence="ECO:0000250"
FT CONFLICT 49
FT /note="E -> G (in Ref. 4; AAM67273)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 129 AA; 14466 MW; 8B4DD5C3AC76F0B2 CRC64;
MAITKKKLVV YTFTLLFIIS YVHCQSTSAS SPGFDNGEVC KQFKFNPCER GGDRGCTVFC
TRKLFTRGEC RDEGCWCCPS FDIGESCQGF KFNPCERGGD RGCTVFCKRK LVTRGECRDE
GCWCCPGQV
