ID   DF208_ARATH             Reviewed;          82 AA.
AC   Q2V2Q8;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 2.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Defensin-like protein 208;
DE   Flags: Precursor;
GN   OrderedLocusNames=At1g34047; ORFNames=F12G12;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17229318; DOI=10.1186/1471-2164-8-18;
RA   Moskal W.A. Jr., Wu H.C., Underwood B.A., Wang W., Town C.D., Xiao Y.-L.;
RT   "Experimental validation of novel genes predicted in the un-annotated
RT   regions of the Arabidopsis genome.";
RL   BMC Genomics 8:18-18(2007).
RN   [4]
RP   GENE FAMILY.
RX   PubMed=15955924; DOI=10.1104/pp.105.060079;
RA   Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT   "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL   Plant Physiol. 138:600-610(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=1;
CC         Comment=A number of isoforms are produced. According to EST
CC         sequences.;
CC       Name=1;
CC         IsoId=Q2V2Q8-1; Sequence=Displayed;
CC   -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC   -!- CAUTION: Lacks 1 of the 4 disulfide bonds, which are conserved features
CC       of the family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AC015446; Type=Frameshift; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AC015446; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002684; AEE31664.1; -; Genomic_DNA.
DR   EMBL; EF182862; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; NP_001031138.4; NM_001036061.4. [Q2V2Q8-1]
DR   AlphaFoldDB; Q2V2Q8; -.
DR   SMR; Q2V2Q8; -.
DR   STRING; 3702.AT1G34047.2; -.
DR   PaxDb; Q2V2Q8; -.
DR   PRIDE; Q2V2Q8; -.
DR   EnsemblPlants; AT1G34047.1; AT1G34047.1; AT1G34047. [Q2V2Q8-1]
DR   GeneID; 3766907; -.
DR   Gramene; AT1G34047.1; AT1G34047.1; AT1G34047. [Q2V2Q8-1]
DR   KEGG; ath:AT1G34047; -.
DR   Araport; AT1G34047; -.
DR   eggNOG; KOG1075; Eukaryota.
DR   InParanoid; Q2V2Q8; -.
DR   OrthoDB; 1630176at2759; -.
DR   PhylomeDB; Q2V2Q8; -.
DR   PRO; PR:Q2V2Q8; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q2V2Q8; baseline and differential.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Alternative splicing; Antimicrobial; Disulfide bond; Fungicide;
KW   Plant defense; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000255"
FT   CHAIN           30..82
FT                   /note="Defensin-like protein 208"
FT                   /id="PRO_0000379700"
FT   DISULFID        38..63
FT                   /evidence="ECO:0000250"
FT   DISULFID        50..76
FT                   /evidence="ECO:0000250"
FT   DISULFID        54..78
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   82 AA;  8424 MW;  350A631905732FC3 CRC64;
     MAKNLNTVSF TVLLLVLLMA STGILETEAA CFKFLGECGA VPFPGTNADC TSCCVGNFGS
     AVCAGRVEVE GGVKHCHCYG TS