ID   DF219_ARATH             Reviewed;          98 AA.
AC   Q2V305;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Defensin-like protein 219;
DE   Flags: Precursor;
GN   OrderedLocusNames=At5g48595; ORFNames=K15N18;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9872454; DOI=10.1093/dnares/5.5.297;
RA   Nakamura Y., Sato S., Asamizu E., Kaneko T., Kotani H., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. VII. Sequence
RT   features of the regions of 1,013,767 bp covered by sixteen physically
RT   assigned P1 and TAC clones.";
RL   DNA Res. 5:297-308(1998).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY.
RX   PubMed=15955924; DOI=10.1104/pp.105.060079;
RA   Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT   "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL   Plant Physiol. 138:600-610(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC   -!- CAUTION: Lacks 1 of the 4 disulfide bonds, which are conserved features
CC       of the family. {ECO:0000305}.
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DR   EMBL; AB015468; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002688; AED95693.1; -; Genomic_DNA.
DR   RefSeq; NP_001032035.1; NM_001036958.1.
DR   AlphaFoldDB; Q2V305; -.
DR   SMR; Q2V305; -.
DR   STRING; 3702.AT5G48595.1; -.
DR   PaxDb; Q2V305; -.
DR   PRIDE; Q2V305; -.
DR   ProteomicsDB; 224231; -.
DR   EnsemblPlants; AT5G48595.1; AT5G48595.1; AT5G48595.
DR   GeneID; 3771465; -.
DR   Gramene; AT5G48595.1; AT5G48595.1; AT5G48595.
DR   KEGG; ath:AT5G48595; -.
DR   Araport; AT5G48595; -.
DR   TAIR; locus:1009023458; AT5G48595.
DR   HOGENOM; CLU_180309_0_0_1; -.
DR   OMA; NIAHCEN; -.
DR   OrthoDB; 1610746at2759; -.
DR   PhylomeDB; Q2V305; -.
DR   PRO; PR:Q2V305; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q2V305; baseline.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255"
FT   CHAIN           17..98
FT                   /note="Defensin-like protein 219"
FT                   /id="PRO_0000379711"
FT   DISULFID        68..85
FT                   /evidence="ECO:0000250"
FT   DISULFID        71..90
FT                   /evidence="ECO:0000250"
FT   DISULFID        75..92
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   98 AA;  11019 MW;  A0514A6A05D9E9BE CRC64;
     MKTIFVFLTL AVLVSSFFKK LFLRASNIMI KSISEGKSQF SGPALSPNID PADEHIGHSP
     EDMKIIFCQQ CAFHCIEKKK NIAHCENSIC RCTLEDIL