DF226_ARATH
ID DF226_ARATH Reviewed; 92 AA.
AC P82621;
DT 13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 88.
DE RecName: Full=Defensin-like protein 226;
DE AltName: Full=S locus cysteine-rich-like protein 2;
DE Short=Protein SCRL2;
DE Short=SCR-like protein 2;
DE Flags: Precursor;
GN Name=SCRL2; OrderedLocusNames=At1g65113; ORFNames=T23K8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000305};
RN [1] {ECO:0000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 31-92.
RC STRAIN=cv. Columbia;
RX PubMed=17565583; DOI=10.1111/j.1365-313x.2007.03136.x;
RA Silverstein K.A.T., Moskal W.A. Jr., Wu H.C., Underwood B.A., Graham M.A.,
RA Town C.D., VandenBosch K.A.;
RT "Small cysteine-rich peptides resembling antimicrobial peptides have been
RT under-predicted in plants.";
RL Plant J. 51:262-280(2007).
RN [4] {ECO:0000305}
RP IDENTIFICATION.
RX PubMed=11437247; DOI=10.1023/a:1010664704926;
RA Vanoosthuyse V., Miege C., Dumas C., Cock J.M.;
RT "Two large Arabidopsis thaliana gene families are homologous to the
RT Brassica gene superfamily that encodes pollen coat proteins and the male
RT component of the self-incompatibility response.";
RL Plant Mol. Biol. 46:17-34(2001).
RN [5]
RP GENE FAMILY.
RX PubMed=15955924; DOI=10.1104/pp.105.060079;
RA Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL Plant Physiol. 138:600-610(2005).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
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DR EMBL; AC007230; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002684; AEE34332.1; -; Genomic_DNA.
DR EMBL; EF182847; -; NOT_ANNOTATED_CDS; mRNA.
DR RefSeq; NP_001031236.1; NM_001036159.3.
DR AlphaFoldDB; P82621; -.
DR SMR; P82621; -.
DR STRING; 3702.AT1G65113.1; -.
DR PaxDb; P82621; -.
DR PRIDE; P82621; -.
DR ProteomicsDB; 224147; -.
DR EnsemblPlants; AT1G65113.1; AT1G65113.1; AT1G65113.
DR GeneID; 3767635; -.
DR Gramene; AT1G65113.1; AT1G65113.1; AT1G65113.
DR KEGG; ath:AT1G65113; -.
DR Araport; AT1G65113; -.
DR TAIR; locus:1009023071; AT1G65113.
DR HOGENOM; CLU_174283_0_0_1; -.
DR OMA; RCECSQR; -.
DR OrthoDB; 1622132at2759; -.
DR PhylomeDB; P82621; -.
DR PRO; PR:P82621; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; P82621; baseline.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR InterPro; IPR010682; SCRL.
DR PANTHER; PTHR34450; PTHR34450; 1.
DR Pfam; PF06876; SCRL; 1.
PE 3: Inferred from homology;
KW Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..27
FT /evidence="ECO:0000255"
FT CHAIN 28..92
FT /note="Defensin-like protein 226"
FT /id="PRO_0000031928"
FT DISULFID 33..92
FT /evidence="ECO:0000250"
FT DISULFID 43..71
FT /evidence="ECO:0000250"
FT DISULFID 51..86
FT /evidence="ECO:0000250"
FT DISULFID 69..88
FT /evidence="ECO:0000250"
SQ SEQUENCE 92 AA; 10469 MW; 2CE7EC9F5981FE85 CRC64;
MKCGVLFMIS CLLITFLVLS HVREVESKTK WGCDMNRPFP GKCGTNGKDT CISDIKKMPG
APKDLVVRCE CSQRFVWKGY PPERLCKCQY DC
