DF250_ARATH
ID DF250_ARATH Reviewed; 89 AA.
AC P82627;
DT 13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Defensin-like protein 250;
DE AltName: Full=S locus cysteine-rich-like protein 8;
DE Short=Protein SCRL8;
DE Short=SCR-like protein 8;
DE Flags: Precursor;
GN Name=SCRL8; OrderedLocusNames=At1g60983; ORFNames=T7P1;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000305};
RN [1] {ECO:0000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3] {ECO:0000305}
RP IDENTIFICATION.
RX PubMed=11437247; DOI=10.1023/a:1010664704926;
RA Vanoosthuyse V., Miege C., Dumas C., Cock J.M.;
RT "Two large Arabidopsis thaliana gene families are homologous to the
RT Brassica gene superfamily that encodes pollen coat proteins and the male
RT component of the self-incompatibility response.";
RL Plant Mol. Biol. 46:17-34(2001).
RN [4]
RP GENE FAMILY.
RX PubMed=15955924; DOI=10.1104/pp.105.060079;
RA Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL Plant Physiol. 138:600-610(2005).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
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DR EMBL; AC018908; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002684; AEE33756.1; -; Genomic_DNA.
DR RefSeq; NP_001031212.1; NM_001036135.1.
DR AlphaFoldDB; P82627; -.
DR PaxDb; P82627; -.
DR PRIDE; P82627; -.
DR EnsemblPlants; AT1G60983.1; AT1G60983.1; AT1G60983.
DR GeneID; 3767591; -.
DR Gramene; AT1G60983.1; AT1G60983.1; AT1G60983.
DR KEGG; ath:AT1G60983; -.
DR Araport; AT1G60983; -.
DR TAIR; locus:1009023065; AT1G60983.
DR HOGENOM; CLU_174283_0_0_1; -.
DR OMA; DIGDLCP; -.
DR OrthoDB; 1574952at2759; -.
DR PhylomeDB; P82627; -.
DR PRO; PR:P82627; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; P82627; baseline and differential.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR InterPro; IPR010682; SCRL.
DR PANTHER; PTHR34450; PTHR34450; 1.
DR Pfam; PF06876; SCRL; 1.
PE 3: Inferred from homology;
KW Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..89
FT /note="Defensin-like protein 250"
FT /id="PRO_0000031934"
FT DISULFID 29..86
FT /evidence="ECO:0000250"
FT DISULFID 40..69
FT /evidence="ECO:0000250"
FT DISULFID 48..79
FT /evidence="ECO:0000250"
FT DISULFID 67..81
FT /evidence="ECO:0000250"
SQ SEQUENCE 89 AA; 10183 MW; E7B19B65AEAB497F CRC64;
MKLAAIFLVS CVLLSLLPSL TIAEKRPWCP TRKQIFDGSC NRTDYTQCFN DLRNTWDDIG
DLCPTDCTCT PQPQNKRLCY CRYLPCPST
