ID   DF268_ARATH             Reviewed;         103 AA.
AC   Q2V4N6; A0MJU3;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Defensin-like protein 268;
DE   Flags: Precursor;
GN   OrderedLocusNames=At1g13605; ORFNames=F13B4, F21F23;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA   Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT   "Simultaneous high-throughput recombinational cloning of open reading
RT   frames in closed and open configurations.";
RL   Plant Biotechnol. J. 4:317-324(2006).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17565583; DOI=10.1111/j.1365-313x.2007.03136.x;
RA   Silverstein K.A.T., Moskal W.A. Jr., Wu H.C., Underwood B.A., Graham M.A.,
RA   Town C.D., VandenBosch K.A.;
RT   "Small cysteine-rich peptides resembling antimicrobial peptides have been
RT   under-predicted in plants.";
RL   Plant J. 51:262-280(2007).
RN   [5]
RP   GENE FAMILY.
RX   PubMed=15955924; DOI=10.1104/pp.105.060079;
RA   Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT   "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL   Plant Physiol. 138:600-610(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABK27948.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AC027134; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC027656; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002684; AEE29041.1; -; Genomic_DNA.
DR   EMBL; DQ912189; ABI34008.1; -; mRNA.
DR   EMBL; DQ912242; ABK27948.1; ALT_SEQ; mRNA.
DR   EMBL; EF182777; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; NP_001031038.1; NM_001035961.3.
DR   AlphaFoldDB; Q2V4N6; -.
DR   PaxDb; Q2V4N6; -.
DR   PRIDE; Q2V4N6; -.
DR   ProteomicsDB; 224255; -.
DR   EnsemblPlants; AT1G13605.1; AT1G13605.1; AT1G13605.
DR   GeneID; 3766718; -.
DR   Gramene; AT1G13605.1; AT1G13605.1; AT1G13605.
DR   KEGG; ath:AT1G13605; -.
DR   Araport; AT1G13605; -.
DR   TAIR; locus:1009023074; AT1G13605.
DR   HOGENOM; CLU_163606_0_0_1; -.
DR   InParanoid; Q2V4N6; -.
DR   OMA; CKYKVCI; -.
DR   OrthoDB; 1567285at2759; -.
DR   PRO; PR:Q2V4N6; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q2V4N6; baseline and differential.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..103
FT                   /note="Defensin-like protein 268"
FT                   /id="PRO_0000379730"
FT   DISULFID        44..103
FT                   /evidence="ECO:0000250"
FT   DISULFID        68..87
FT                   /evidence="ECO:0000250"
FT   DISULFID        74..98
FT                   /evidence="ECO:0000250"
FT   DISULFID        78..100
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   103 AA;  11697 MW;  AA1FCE14CBF6BFEF CRC64;
     MARLIFHFVF ALILAAYLLS VTDAIPRGWQ EPCFCPSKNP YCDCGDDLQV PTTSVISPKP
     IIEQCARCER NSQCNKVCPA TCKYKVCIFN RTCEFSTCHC YRC