ID   DF281_ARATH             Reviewed;          78 AA.
AC   Q2V4C3;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Defensin-like protein 281;
DE   Flags: Precursor;
GN   OrderedLocusNames=At1g77093; ORFNames=F22K20;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY.
RX   PubMed=15955924; DOI=10.1104/pp.105.060079;
RA   Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT   "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL   Plant Physiol. 138:600-610(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC   -!- CAUTION: Lacks 1 of the 4 disulfide bonds, which are conserved features
CC       of the family. {ECO:0000305}.
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DR   EMBL; AC002291; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002684; AEE35934.1; -; Genomic_DNA.
DR   RefSeq; NP_001031290.1; NM_001036213.2.
DR   AlphaFoldDB; Q2V4C3; -.
DR   SMR; Q2V4C3; -.
DR   PaxDb; Q2V4C3; -.
DR   PRIDE; Q2V4C3; -.
DR   ProteomicsDB; 224258; -.
DR   EnsemblPlants; AT1G77093.1; AT1G77093.1; AT1G77093.
DR   GeneID; 3767714; -.
DR   Gramene; AT1G77093.1; AT1G77093.1; AT1G77093.
DR   KEGG; ath:AT1G77093; -.
DR   Araport; AT1G77093; -.
DR   TAIR; locus:1009023102; AT1G77093.
DR   HOGENOM; CLU_2761249_0_0_1; -.
DR   PhylomeDB; Q2V4C3; -.
DR   PRO; PR:Q2V4C3; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q2V4C3; baseline.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..78
FT                   /note="Defensin-like protein 281"
FT                   /id="PRO_0000379742"
FT   DISULFID        37..60
FT                   /evidence="ECO:0000250"
FT   DISULFID        46..72
FT                   /evidence="ECO:0000250"
FT   DISULFID        50..74
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   78 AA;  8609 MW;  A1DB5EE951B1D903 CRC64;
     MASTKYLVLL FICLSVLLTP GLGTDPVPTP PGLHIPCGKG FTSKECNKYC TGVGYRRGYC
     APDEEYPQIS SCYCKWRI