ID   DF286_ARATH             Reviewed;          72 AA.
AC   Q2L6T6;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   21-FEB-2006, sequence version 1.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Defensin-like protein 286;
DE   Flags: Precursor;
GN   OrderedLocusNames=At1g13607; ORFNames=F13B4, F21F23;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA   Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT   "Simultaneous high-throughput recombinational cloning of open reading
RT   frames in closed and open configurations.";
RL   Plant Biotechnol. J. 4:317-324(2006).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17565583; DOI=10.1111/j.1365-313x.2007.03136.x;
RA   Silverstein K.A.T., Moskal W.A. Jr., Wu H.C., Underwood B.A., Graham M.A.,
RA   Town C.D., VandenBosch K.A.;
RT   "Small cysteine-rich peptides resembling antimicrobial peptides have been
RT   under-predicted in plants.";
RL   Plant J. 51:262-280(2007).
RN   [5]
RP   GENE FAMILY.
RX   PubMed=15955924; DOI=10.1104/pp.105.060079;
RA   Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT   "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL   Plant Physiol. 138:600-610(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC   -!- CAUTION: Lacks 1 of the 4 disulfide bonds, which are conserved features
CC       of the family. {ECO:0000305}.
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DR   EMBL; AC027134; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC027656; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002684; AEE29042.1; -; Genomic_DNA.
DR   EMBL; DQ912190; ABI34009.1; -; mRNA.
DR   EMBL; EF182778; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; NP_001031039.1; NM_001035962.3.
DR   AlphaFoldDB; Q2L6T6; -.
DR   SMR; Q2L6T6; -.
DR   PaxDb; Q2L6T6; -.
DR   PRIDE; Q2L6T6; -.
DR   ProteomicsDB; 224643; -.
DR   EnsemblPlants; AT1G13607.1; AT1G13607.1; AT1G13607.
DR   GeneID; 3766719; -.
DR   Gramene; AT1G13607.1; AT1G13607.1; AT1G13607.
DR   KEGG; ath:AT1G13607; -.
DR   Araport; AT1G13607; -.
DR   TAIR; locus:1009023064; AT1G13607.
DR   HOGENOM; CLU_2625318_0_0_1; -.
DR   OMA; SYRNCKC; -.
DR   OrthoDB; 1858313at2759; -.
DR   PRO; PR:Q2L6T6; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q2L6T6; baseline and differential.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..72
FT                   /note="Defensin-like protein 286"
FT                   /id="PRO_0000379746"
FT   DISULFID        41..63
FT                   /evidence="ECO:0000250"
FT   DISULFID        47..68
FT                   /evidence="ECO:0000250"
FT   DISULFID        53..70
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   72 AA;  8223 MW;  F88AEA95E2731460 CRC64;
     MNNFRITIVA FLAVLVFTTT VTNSLDEPNM DTISKSREYK CKIDLDCSNH IACRHCSYRN
     CKCDHGTCKC MP