ID   DF293_ARATH             Reviewed;          90 AA.
AC   Q2V4A3;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Defensin-like protein 293;
DE   Flags: Precursor;
GN   OrderedLocusNames=At2g04925; ORFNames=F1O13;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA   Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT   "Simultaneous high-throughput recombinational cloning of open reading
RT   frames in closed and open configurations.";
RL   Plant Biotechnol. J. 4:317-324(2006).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17565583; DOI=10.1111/j.1365-313x.2007.03136.x;
RA   Silverstein K.A.T., Moskal W.A. Jr., Wu H.C., Underwood B.A., Graham M.A.,
RA   Town C.D., VandenBosch K.A.;
RT   "Small cysteine-rich peptides resembling antimicrobial peptides have been
RT   under-predicted in plants.";
RL   Plant J. 51:262-280(2007).
RN   [5]
RP   GENE FAMILY.
RX   PubMed=15955924; DOI=10.1104/pp.105.060079;
RA   Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT   "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL   Plant Physiol. 138:600-610(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC   -!- CAUTION: Lacks 1 of the 4 disulfide bonds, which are conserved features
CC       of the family. {ECO:0000305}.
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DR   EMBL; AC007211; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002685; AEC05888.1; -; Genomic_DNA.
DR   EMBL; DQ912216; ABI34022.1; -; mRNA.
DR   EMBL; EF182806; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; NP_001031322.1; NM_001036245.3.
DR   AlphaFoldDB; Q2V4A3; -.
DR   PaxDb; Q2V4A3; -.
DR   PRIDE; Q2V4A3; -.
DR   ProteomicsDB; 224262; -.
DR   EnsemblPlants; AT2G04925.1; AT2G04925.1; AT2G04925.
DR   GeneID; 3768556; -.
DR   Gramene; AT2G04925.1; AT2G04925.1; AT2G04925.
DR   KEGG; ath:AT2G04925; -.
DR   Araport; AT2G04925; -.
DR   TAIR; locus:1009023214; AT2G04925.
DR   HOGENOM; CLU_2416386_0_0_1; -.
DR   InParanoid; Q2V4A3; -.
DR   OMA; RCEKNAG; -.
DR   OrthoDB; 1615221at2759; -.
DR   PhylomeDB; Q2V4A3; -.
DR   PRO; PR:Q2V4A3; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q2V4A3; baseline and differential.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255"
FT   CHAIN           27..90
FT                   /note="Defensin-like protein 293"
FT                   /id="PRO_0000379753"
FT   DISULFID        63..83
FT                   /evidence="ECO:0000250"
FT   DISULFID        69..88
FT                   /evidence="ECO:0000250"
FT   DISULFID        75..90
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   90 AA;  10029 MW;  E5C3BECA50C17B87 CRC64;
     MTSRAKSLFI FFFLISCTFM LLETDASRNK LSSYIPLCGS NTYCGGLWCP KKGGKYSCIS
     MSCDIQEDCP KLVRCKNSPG PYCMEGFCTC