DF295_ARATH
ID DF295_ARATH Reviewed; 111 AA.
AC Q4VNZ6;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 2.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=Defensin-like protein 295;
DE Flags: Precursor;
GN OrderedLocusNames=At2g04045; ORFNames=F3L12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17229318; DOI=10.1186/1471-2164-8-18;
RA Moskal W.A. Jr., Wu H.C., Underwood B.A., Wang W., Town C.D., Xiao Y.-L.;
RT "Experimental validation of novel genes predicted in the un-annotated
RT regions of the Arabidopsis genome.";
RL BMC Genomics 8:18-18(2007).
RN [4]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 2-101, AND GENE FAMILY.
RX PubMed=15955924; DOI=10.1104/pp.105.060079;
RA Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL Plant Physiol. 138:600-610(2005).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC -!- CAUTION: Contains 6 disulfide bonds instead of the 4 disulfide bonds,
CC which are conserved features of the family. {ECO:0000305}.
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DR EMBL; AC007178; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002685; AEC05785.1; -; Genomic_DNA.
DR EMBL; EF182864; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; AY803266; AAX39307.1; -; mRNA.
DR RefSeq; NP_001031316.1; NM_001036239.3.
DR AlphaFoldDB; Q4VNZ6; -.
DR PaxDb; Q4VNZ6; -.
DR PRIDE; Q4VNZ6; -.
DR EnsemblPlants; AT2G04045.1; AT2G04045.1; AT2G04045.
DR GeneID; 3768428; -.
DR Gramene; AT2G04045.1; AT2G04045.1; AT2G04045.
DR KEGG; ath:AT2G04045; -.
DR Araport; AT2G04045; -.
DR TAIR; locus:1009023220; AT2G04045.
DR HOGENOM; CLU_172799_0_0_1; -.
DR InParanoid; Q4VNZ6; -.
DR OMA; DPRMRFT; -.
DR OrthoDB; 1563549at2759; -.
DR PhylomeDB; Q4VNZ6; -.
DR PRO; PR:Q4VNZ6; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q4VNZ6; baseline.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..28
FT /evidence="ECO:0000255"
FT CHAIN 29..111
FT /note="Defensin-like protein 295"
FT /id="PRO_0000379755"
FT DISULFID 34..52
FT /evidence="ECO:0000250"
FT DISULFID 40..57
FT /evidence="ECO:0000250"
FT DISULFID 45..59
FT /evidence="ECO:0000250"
FT DISULFID 81..102
FT /evidence="ECO:0000250"
FT DISULFID 87..107
FT /evidence="ECO:0000250"
FT DISULFID 95..109
FT /evidence="ECO:0000250"
FT CONFLICT 21
FT /note="L -> S (in Ref. 4; AAX39307)"
FT /evidence="ECO:0000305"
FT CONFLICT 48
FT /note="G -> E (in Ref. 4; AAX39307)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 111 AA; 12551 MW; 40BFC04CF28414CF CRC64;
MASKITFVFL VVVVINCAMM LSMPTAEAHN FLPCVITNDC EYHHCSSGTV LCVNRQCHCS
RSSTHQTKLD NLKKMDYAKK CKWTKDCDPR MRFTCVSGSY MCFDGLCTCT N
