DF296_ARATH
ID DF296_ARATH Reviewed; 110 AA.
AC Q4VNZ5;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 2.
DT 03-AUG-2022, entry version 67.
DE RecName: Full=Defensin-like protein 296;
DE Flags: Precursor;
GN OrderedLocusNames=At2g04046; ORFNames=F3L12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 2-101, AND GENE FAMILY.
RX PubMed=15955924; DOI=10.1104/pp.105.060079;
RA Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL Plant Physiol. 138:600-610(2005).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC -!- CAUTION: Contains 6 disulfide bonds instead of the 4 disulfide bonds,
CC which are conserved features of the family. {ECO:0000305}.
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DR EMBL; AC007178; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002685; AEC05786.1; -; Genomic_DNA.
DR EMBL; AY803267; AAX39308.1; -; mRNA.
DR RefSeq; NP_001031317.1; NM_001036240.2.
DR AlphaFoldDB; Q4VNZ5; -.
DR SMR; Q4VNZ5; -.
DR PaxDb; Q4VNZ5; -.
DR PRIDE; Q4VNZ5; -.
DR EnsemblPlants; AT2G04046.1; AT2G04046.1; AT2G04046.
DR GeneID; 3768429; -.
DR Gramene; AT2G04046.1; AT2G04046.1; AT2G04046.
DR KEGG; ath:AT2G04046; -.
DR Araport; AT2G04046; -.
DR TAIR; locus:1009023175; AT2G04046.
DR HOGENOM; CLU_172799_0_0_1; -.
DR OMA; MNDAKTC; -.
DR OrthoDB; 1548526at2759; -.
DR PhylomeDB; Q4VNZ5; -.
DR PRO; PR:Q4VNZ5; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q4VNZ5; baseline and differential.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..28
FT /evidence="ECO:0000255"
FT CHAIN 29..110
FT /note="Defensin-like protein 296"
FT /id="PRO_0000379756"
FT DISULFID 34..52
FT /evidence="ECO:0000250"
FT DISULFID 40..57
FT /evidence="ECO:0000250"
FT DISULFID 45..59
FT /evidence="ECO:0000250"
FT DISULFID 81..102
FT /evidence="ECO:0000250"
FT DISULFID 87..107
FT /evidence="ECO:0000250"
FT DISULFID 95..109
FT /evidence="ECO:0000250"
SQ SEQUENCE 110 AA; 12067 MW; 99E7870A85F5343A CRC64;
MASKITIFFV LALVVVCTMM VCIPTATAEL VLPCKTTYDC VNLPCLGRPP LCINGQCKCT
TTLTHQAKLD NLRTMNDAKT CKYTSDCDPR MRYSCVSGSY ICLNGFCTCT
