DF298_ARATH
ID DF298_ARATH Reviewed; 102 AA.
AC Q2V459;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-JAN-2006, sequence version 1.
DT 03-AUG-2022, entry version 71.
DE RecName: Full=Putative defensin-like protein 298;
DE Flags: Precursor;
GN OrderedLocusNames=At2g25185; ORFNames=T22F11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=15955924; DOI=10.1104/pp.105.060079;
RA Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL Plant Physiol. 138:600-610(2005).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC -!- CAUTION: Contains 6 disulfide bonds instead of the 4 disulfide bonds,
CC which are conserved features of the family. {ECO:0000305}.
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DR EMBL; AC007070; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002685; AEC07668.1; -; Genomic_DNA.
DR RefSeq; NP_001031411.1; NM_001036334.2.
DR AlphaFoldDB; Q2V459; -.
DR STRING; 3702.AT2G25185.1; -.
DR PaxDb; Q2V459; -.
DR ProteomicsDB; 224651; -.
DR EnsemblPlants; AT2G25185.1; AT2G25185.1; AT2G25185.
DR GeneID; 3768529; -.
DR Gramene; AT2G25185.1; AT2G25185.1; AT2G25185.
DR KEGG; ath:AT2G25185; -.
DR Araport; AT2G25185; -.
DR TAIR; locus:1009023232; AT2G25185.
DR eggNOG; ENOG502R2CG; Eukaryota.
DR HOGENOM; CLU_172799_0_0_1; -.
DR OMA; IVPCKTS; -.
DR OrthoDB; 1557817at2759; -.
DR PhylomeDB; Q2V459; -.
DR PRO; PR:Q2V459; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q2V459; baseline and differential.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..29
FT /evidence="ECO:0000255"
FT CHAIN 30..102
FT /note="Putative defensin-like protein 298"
FT /id="PRO_0000379757"
FT DISULFID 35..53
FT /evidence="ECO:0000250"
FT DISULFID 41..58
FT /evidence="ECO:0000250"
FT DISULFID 46..60
FT /evidence="ECO:0000250"
FT DISULFID 74..93
FT /evidence="ECO:0000250"
FT DISULFID 80..98
FT /evidence="ECO:0000250"
FT DISULFID 86..100
FT /evidence="ECO:0000250"
SQ SEQUENCE 102 AA; 10861 MW; FD67A2FB5992E9C9 CRC64;
MSASKATMLI LFALFLSDIL LVSIPRAEAQ LIVPCKTSEQ CKSIRCSNGS AQCVNKQCQC
PSLKQIYSVT DVSCKTVSDC VASHQCPTGL SACIEGKCIC LP
