ID   DF301_ARATH             Reviewed;          97 AA.
AC   Q3E715;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Defensin-like protein 301;
DE   Flags: Precursor;
GN   OrderedLocusNames=At5g04045; ORFNames=F8F6;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130714; DOI=10.1038/35048507;
RA   Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA   Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA   Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA   Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA   O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA   Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA   Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA   Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA   Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA   Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA   Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA   Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA   Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA   Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA   Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA   McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA   Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA   Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA   Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA   Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA   Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA   Bevan M., Fransz P.F.;
RT   "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL   Nature 408:823-826(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14993207; DOI=10.1101/gr.1515604;
RA   Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA   Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA   Weissenbach J., Salanoubat M.;
RT   "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT   combined approach to evaluate and improve Arabidopsis genome annotation.";
RL   Genome Res. 14:406-413(2004).
RN   [4]
RP   GENE FAMILY.
RX   PubMed=15955924; DOI=10.1104/pp.105.060079;
RA   Silverstein K.A.T., Graham M.A., Paape T.D., VandenBosch K.A.;
RT   "Genome organization of more than 300 defensin-like genes in Arabidopsis.";
RL   Plant Physiol. 138:600-610(2005).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the DEFL family. {ECO:0000305}.
CC   -!- CAUTION: Contains 6 disulfide bonds instead of the 4 disulfide bonds,
CC       which are conserved features of the family. {ECO:0000305}.
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DR   EMBL; AL162873; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002688; AED90688.1; -; Genomic_DNA.
DR   EMBL; BX833563; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; NP_974727.1; NM_202998.2.
DR   AlphaFoldDB; Q3E715; -.
DR   PaxDb; Q3E715; -.
DR   PRIDE; Q3E715; -.
DR   EnsemblPlants; AT5G04045.1; AT5G04045.1; AT5G04045.
DR   GeneID; 2745976; -.
DR   Gramene; AT5G04045.1; AT5G04045.1; AT5G04045.
DR   KEGG; ath:AT5G04045; -.
DR   Araport; AT5G04045; -.
DR   TAIR; locus:1006230523; AT5G04045.
DR   HOGENOM; CLU_2389210_0_0_1; -.
DR   InParanoid; Q3E715; -.
DR   OMA; NSHVICD; -.
DR   OrthoDB; 1604463at2759; -.
DR   PhylomeDB; Q3E715; -.
DR   PRO; PR:Q3E715; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q3E715; baseline and differential.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Antimicrobial; Disulfide bond; Fungicide; Plant defense;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..97
FT                   /note="Defensin-like protein 301"
FT                   /id="PRO_0000379758"
FT   DISULFID        28..47
FT                   /evidence="ECO:0000250"
FT   DISULFID        34..53
FT                   /evidence="ECO:0000250"
FT   DISULFID        39..55
FT                   /evidence="ECO:0000250"
FT   DISULFID        65..84
FT                   /evidence="ECO:0000250"
FT   DISULFID        71..92
FT                   /evidence="ECO:0000250"
FT   DISULFID        76..94
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   97 AA;  10401 MW;  46421D539EA217E4 CRC64;
     MEKVTSIFFV LLLISSCLIL RSQGQFRCKS VAECDSRGCR VGTHVICNEH HICTCAHGSP
     IGGQCDGVED CDLSGCPPNS HVICDRIGGN FCTCVPN