ID   DFP1_LONON              Reviewed;         168 AA.
AC   Q5MGQ0;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 26.
DE   RecName: Full=Putative defense protein 1;
DE            Short=DFP-1;
DE   Flags: Precursor;
OS   Lonomia obliqua (Moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Saturniidae; Hemileucinae; Lonomia.
OX   NCBI_TaxID=304329;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Tegument;
RX   PubMed=16023793; DOI=10.1016/j.gene.2005.05.002;
RA   Veiga A.B.G., Ribeiro J.M.C., Guimaraes J.A., Francischetti I.M.B.;
RT   "A catalog for the transcripts from the venomous structures of the
RT   caterpillar Lonomia obliqua: identification of the proteins potentially
RT   involved in the coagulation disorder and hemorrhagic syndrome.";
RL   Gene 355:11-27(2005).
CC   -!- FUNCTION: May have antimicrobial activity. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the insect defense protein family.
CC       {ECO:0000305}.
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DR   EMBL; AY829736; AAV91350.1; -; mRNA.
DR   AlphaFoldDB; Q5MGQ0; -.
DR   SMR; Q5MGQ0; -.
DR   GO; GO:0005576; C:extracellular region; ISS:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0042832; P:defense response to protozoan; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   CDD; cd08544; Reeler; 1.
DR   Gene3D; 2.60.40.4060; -; 1.
DR   InterPro; IPR002861; Reeler_dom.
DR   InterPro; IPR042307; Reeler_sf.
DR   Pfam; PF02014; Reeler; 1.
DR   PROSITE; PS51019; REELIN; 1.
PE   2: Evidence at transcript level;
KW   Antibiotic; Antimicrobial; Disulfide bond; Immunity; Innate immunity;
KW   Secreted; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..168
FT                   /note="Putative defense protein 1"
FT                   /id="PRO_0000372772"
FT   DOMAIN          19..168
FT                   /note="Reelin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00363"
FT   DISULFID        28..105
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   168 AA;  17801 MW;  72189C30206573B8 CRC64;
     MMFIYVVALV SAVAFTDAFP TGAPVSACFD MIPGHGTDPK PPPAPYTIGA VANSVKAGKS
     VEVVISGKTP EDTMLGILLE ARQGDKIVGT WNVAPDDDFA QLLDCGAPGN AVTHKHVPNK
     QPKQTVSYVW NAPADGEGDV TFLVTIVKKY DTFWVKVSSA PIQIVHAH