ID   DFP2_ANTMY              Reviewed;         161 AA.
AC   P0C963;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   25-MAY-2022, entry version 19.
DE   RecName: Full=Putative defense protein 2;
DE            Short=DFP-2;
DE   Flags: Precursor; Fragment;
OS   Antheraea mylitta (Tasar silkworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Saturniidae; Saturniinae; Saturniini; Antheraea.
OX   NCBI_TaxID=34739;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Fat body;
RX   PubMed=16857061; DOI=10.1186/1471-2164-7-184;
RA   Gandhe A.S., Arunkumar K.P., John S.H., Nagaraju J.;
RT   "Analysis of bacteria-challenged wild silkmoth, Antheraea mylitta
RT   (lepidoptera) transcriptome reveals potential immune genes.";
RL   BMC Genomics 7:184-184(2006).
CC   -!- FUNCTION: May have antimicrobial activity. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the insect defense protein family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; P0C963; -.
DR   SMR; P0C963; -.
DR   GO; GO:0005576; C:extracellular region; ISS:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0042832; P:defense response to protozoan; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   CDD; cd08544; Reeler; 1.
DR   Gene3D; 2.60.40.4060; -; 1.
DR   InterPro; IPR002861; Reeler_dom.
DR   InterPro; IPR042307; Reeler_sf.
DR   Pfam; PF02014; Reeler; 1.
DR   PROSITE; PS51019; REELIN; 1.
PE   2: Evidence at transcript level;
KW   Antibiotic; Antimicrobial; Disulfide bond; Glycoprotein; Immunity;
KW   Innate immunity; Secreted; Signal.
FT   SIGNAL          <1..11
FT                   /evidence="ECO:0000255"
FT   CHAIN           12..161
FT                   /note="Putative defense protein 2"
FT                   /id="PRO_0000372767"
FT   DOMAIN          12..161
FT                   /note="Reelin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00363"
FT   CARBOHYD        91
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        21..98
FT                   /evidence="ECO:0000255"
FT   NON_TER         1
SQ   SEQUENCE   161 AA;  17284 MW;  B5E729E05070B1CF CRC64;
     LSWSALALTS AYPTGAPTSA CFDMIPGHFA SPQSEPAPYI ITTPVSAVKA GDSIEVTISG
     KTAKDTMRGI LLEARQGDKI VGTWTVKPND NFSQLLNCGE PGNAVTHKHH ANSEDKQTVS
     YLWTASGHLE GDVVFKVTIV KDYHTFWVAV PSAPVKILSH H