ID   DFP2_LONON              Reviewed;         113 AA.
AC   Q5MGP9;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 23.
DE   RecName: Full=Defense protein 2;
DE            Short=DFP-2;
DE   Flags: Fragment;
OS   Lonomia obliqua (Moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Saturniidae; Hemileucinae; Lonomia.
OX   NCBI_TaxID=304329;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Tegument;
RX   PubMed=16023793; DOI=10.1016/j.gene.2005.05.002;
RA   Veiga A.B.G., Ribeiro J.M.C., Guimaraes J.A., Francischetti I.M.B.;
RT   "A catalog for the transcripts from the venomous structures of the
RT   caterpillar Lonomia obliqua: identification of the proteins potentially
RT   involved in the coagulation disorder and hemorrhagic syndrome.";
RL   Gene 355:11-27(2005).
CC   -!- FUNCTION: Has antibacterial activity against both Gram-positive and
CC       Gram-negative bacteria. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the attacin/sarcotoxin-2 family. {ECO:0000305}.
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DR   EMBL; AY829737; AAV91351.1; -; mRNA.
DR   AlphaFoldDB; Q5MGP9; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   InterPro; IPR005521; Attacin_C.
DR   Pfam; PF03769; Attacin_C; 1.
PE   2: Evidence at transcript level;
KW   Antibiotic; Antimicrobial; Immunity; Innate immunity; Secreted.
FT   CHAIN           <1..113
FT                   /note="Defense protein 2"
FT                   /id="PRO_0000372776"
FT   NON_TER         1
SQ   SEQUENCE   113 AA;  12430 MW;  584BF7440E178537 CRC64;
     TGSGKYNILH NDNHNLDLTG KFLECSRSNP NLSDYNKYSA ILDYLYKDKL SASLGVAHSG
     LLDRTDLSAL GKVNLLNDKN TRLDLFGGLT KSMSPKFDSG LKPNFGLQLE SSF