ID   DFP3_ANTMY              Reviewed;         163 AA.
AC   Q0Q028;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 25.
DE   RecName: Full=Putative defense protein 3;
DE            Short=DFP-3;
DE   Flags: Precursor;
OS   Antheraea mylitta (Tasar silkworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Saturniidae; Saturniinae; Saturniini; Antheraea.
OX   NCBI_TaxID=34739;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Fat body;
RX   PubMed=16857061; DOI=10.1186/1471-2164-7-184;
RA   Gandhe A.S., Arunkumar K.P., John S.H., Nagaraju J.;
RT   "Analysis of bacteria-challenged wild silkmoth, Antheraea mylitta
RT   (lepidoptera) transcriptome reveals potential immune genes.";
RL   BMC Genomics 7:184-184(2006).
CC   -!- FUNCTION: May have antimicrobial activity. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the insect defense protein family.
CC       {ECO:0000305}.
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DR   EMBL; DQ666502; ABG72706.1; -; mRNA.
DR   AlphaFoldDB; Q0Q028; -.
DR   SMR; Q0Q028; -.
DR   GO; GO:0005576; C:extracellular region; ISS:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0042832; P:defense response to protozoan; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   CDD; cd08544; Reeler; 1.
DR   Gene3D; 2.60.40.4060; -; 1.
DR   InterPro; IPR002861; Reeler_dom.
DR   InterPro; IPR042307; Reeler_sf.
DR   Pfam; PF02014; Reeler; 1.
DR   PROSITE; PS51019; REELIN; 1.
PE   2: Evidence at transcript level;
KW   Antibiotic; Antimicrobial; Disulfide bond; Immunity; Innate immunity;
KW   Secreted; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..163
FT                   /note="Putative defense protein 3"
FT                   /id="PRO_0000372768"
FT   DOMAIN          19..163
FT                   /note="Reelin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00363"
FT   DISULFID        28..103
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   163 AA;  17508 MW;  2D7C0DA2B8D433A6 CRC64;
     MMFAYIVAVV SALALTSAYP TGAPSSTCVS MRPGHLADPQ PLPAPYTIST PVNTMKAGDS
     IEVTISGNTP DDFFRGILLQ ARQGDNIVGK WTVKDDFSKL LDCGEPDNAV THANSVDKTT
     VSYIWTAPED FVGDVVFLVT IVKVYETFWV AIPSAPVTVL SHK