ID   DFP6_LONON              Reviewed;          75 AA.
AC   Q5MGC9;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 32.
DE   RecName: Full=Defense protein 6;
DE            Short=DFP-6;
DE   Flags: Precursor;
OS   Lonomia obliqua (Moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Saturniidae; Hemileucinae; Lonomia.
OX   NCBI_TaxID=304329;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Spicule;
RX   PubMed=16023793; DOI=10.1016/j.gene.2005.05.002;
RA   Veiga A.B.G., Ribeiro J.M.C., Guimaraes J.A., Francischetti I.M.B.;
RT   "A catalog for the transcripts from the venomous structures of the
RT   caterpillar Lonomia obliqua: identification of the proteins potentially
RT   involved in the coagulation disorder and hemorrhagic syndrome.";
RL   Gene 355:11-27(2005).
CC   -!- FUNCTION: Has antibacterial activity. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the invertebrate defensin family. {ECO:0000305}.
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DR   EMBL; AY829857; AAV91471.1; -; mRNA.
DR   AlphaFoldDB; Q5MGC9; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Antibiotic; Antimicrobial; Cleavage on pair of basic residues; Defensin;
KW   Disulfide bond; Immunity; Innate immunity; Secreted; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   PROPEP          21..32
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000372779"
FT   CHAIN           33..75
FT                   /note="Defense protein 6"
FT                   /id="PRO_0000372780"
FT   DISULFID        44..63
FT                   /evidence="ECO:0000255"
FT   DISULFID        49..68
FT                   /evidence="ECO:0000250"
FT   DISULFID        53..70
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   75 AA;  8194 MW;  6B0E5A0FF280AE98 CRC64;
     MKTCLVFAFF LVAVFAAVQA EENDSPQTLP RRLTVRAAQS FGRCNQKQCD ADCVKKGYFG
     GLCTLTSCFC TGSRS