ID   DFP_BOMMO               Reviewed;         171 AA.
AC   Q008X1;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   14-NOV-2006, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Putative defense protein;
DE   Flags: Precursor;
OS   Bombyx mori (Silk moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Bombycidae; Bombycinae; Bombyx.
OX   NCBI_TaxID=7091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Zhang Y., Xu J., Chen J., Wang D., Nie Z., Lu Z., Jiang C., Liu L.-L.,
RA   Song L., He P., Chen F., Wu X.-F.;
RT   "Construction and analysis of putative protein database based on the cDNA
RT   library.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May have antimicrobial activity. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the insect defense protein family.
CC       {ECO:0000305}.
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DR   EMBL; DQ898221; ABJ09465.1; -; mRNA.
DR   RefSeq; NP_001091819.1; NM_001098349.1.
DR   RefSeq; XP_012546644.1; XM_012691190.1.
DR   AlphaFoldDB; Q008X1; -.
DR   SMR; Q008X1; -.
DR   STRING; 7091.BGIBMGA014360-TA; -.
DR   EnsemblMetazoa; BGIBMGA014360-RA; BGIBMGA014360-TA; BGIBMGA014360.
DR   GeneID; 778525; -.
DR   KEGG; bmor:778525; -.
DR   eggNOG; ENOG502S86D; Eukaryota.
DR   HOGENOM; CLU_091827_2_0_1; -.
DR   InParanoid; Q008X1; -.
DR   OMA; WTEITSS; -.
DR   OrthoDB; 1223313at2759; -.
DR   Proteomes; UP000005204; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; ISS:UniProtKB.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0042832; P:defense response to protozoan; ISS:UniProtKB.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   CDD; cd08544; Reeler; 1.
DR   Gene3D; 2.60.40.4060; -; 1.
DR   InterPro; IPR002861; Reeler_dom.
DR   InterPro; IPR042307; Reeler_sf.
DR   Pfam; PF02014; Reeler; 1.
DR   PROSITE; PS51019; REELIN; 1.
PE   2: Evidence at transcript level;
KW   Antibiotic; Antimicrobial; Disulfide bond; Glycoprotein; Immunity;
KW   Innate immunity; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..171
FT                   /note="Putative defense protein"
FT                   /id="PRO_0000372769"
FT   DOMAIN          24..171
FT                   /note="Reelin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00363"
FT   CARBOHYD        41
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        33..110
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   171 AA;  18482 MW;  F3BBFEB073CA63BA CRC64;
     MKVYACLCAA VVMLVMTSRV SEARSTGAPL SACRDMMPQH NATAQTSPPP YTITTDAQSV
     APGDSVEVVI AGKLPEDTLR GYLLQARQGD DILGTFSLED GDVFSQLINC GKPGNAVTHK
     KHDNKEDKRQ VRVRWSPPQG LTGEVVFRAT IVKTLKVFWV GVQSAPIKIV S