ID   DFX_METTH               Reviewed;         124 AA.
AC   O26851;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Desulfoferrodoxin homolog;
DE            Short=Dfx;
GN   OrderedLocusNames=MTH_757;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
CC   -!- COFACTOR:
CC       Name=Fe(3+); Xref=ChEBI:CHEBI:29034; Evidence={ECO:0000250};
CC       Note=Binds 1 Fe(3+) ion per subunit. The iron ion 1 is coordinated via
CC       4 cysteine residues. {ECO:0000250};
CC   -!- COFACTOR:
CC       Name=Cu(2+); Xref=ChEBI:CHEBI:29036; Evidence={ECO:0000250};
CC       Note=Binds 1 Fe(2+) ion per subunit. The iron ion 2 is coordinated via
CC       four histidines and one cysteine residue. {ECO:0000250};
CC   -!- SIMILARITY: Belongs to the desulfoferrodoxin family. {ECO:0000305}.
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DR   EMBL; AE000666; AAB85260.1; -; Genomic_DNA.
DR   PIR; B69201; B69201.
DR   RefSeq; WP_010876395.1; NC_000916.1.
DR   AlphaFoldDB; O26851; -.
DR   SMR; O26851; -.
DR   STRING; 187420.MTH_757; -.
DR   EnsemblBacteria; AAB85260; AAB85260; MTH_757.
DR   GeneID; 1471165; -.
DR   KEGG; mth:MTH_757; -.
DR   PATRIC; fig|187420.15.peg.744; -.
DR   HOGENOM; CLU_118960_1_0_2; -.
DR   OMA; EEKHYIQ; -.
DR   Proteomes; UP000005223; Chromosome.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0019430; P:removal of superoxide radicals; IEA:InterPro.
DR   CDD; cd00974; DSRD; 1.
DR   Gene3D; 2.20.28.100; -; 1.
DR   Gene3D; 2.60.40.730; -; 1.
DR   InterPro; IPR002742; Desulfoferrodoxin_Fe-bd_dom.
DR   InterPro; IPR036073; Desulfoferrodoxin_Fe-bd_dom_sf.
DR   InterPro; IPR004462; Desulfoferrodoxin_N.
DR   InterPro; IPR038094; Desulfoferrodoxin_N_sf.
DR   InterPro; IPR004793; Desulfoferrodoxin_rbo.
DR   Pfam; PF06397; Desulfoferrod_N; 1.
DR   Pfam; PF01880; Desulfoferrodox; 1.
DR   SUPFAM; SSF49367; SSF49367; 1.
DR   TIGRFAMs; TIGR00319; desulf_FeS4; 1.
DR   TIGRFAMs; TIGR00320; dfx_rbo; 1.
DR   TIGRFAMs; TIGR00332; neela_ferrous; 1.
PE   3: Inferred from homology;
KW   Electron transport; Iron; Metal-binding; Reference proteome; Transport.
FT   CHAIN           1..124
FT                   /note="Desulfoferrodoxin homolog"
FT                   /id="PRO_0000140868"
FT   BINDING         10
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250"
FT   BINDING         13
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250"
FT   BINDING         29
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250"
FT   BINDING         30
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000250"
FT   BINDING         49
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250"
FT   BINDING         69
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250"
FT   BINDING         75
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250"
FT   BINDING         117
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250"
FT   BINDING         120
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   124 AA;  13988 MW;  130CAD6A1B262D48 CRC64;
     MTETNQIFRC NVCGNIVEVL NPGAGQLVCC NQPMELLVAR RTDVGPEKHV PVVEETGTGI
     RVKVGEVPHP MEENHHIQWI EVIAGDMVYR KDLNPGDNPE AEFPVEMASD FMVRIYCNIH
     GLWY