ID   DGDR_BURCE              Reviewed;         294 AA.
AC   P16931;
DT   01-AUG-1990, integrated into UniProtKB/Swiss-Prot.
DT   24-OCT-2003, sequence version 3.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=HTH-type transcriptional regulator DgdR;
DE   AltName: Full=2,2-dialkylglycine decarboxylase repressor;
GN   Name=dgdR;
OS   Burkholderia cepacia (Pseudomonas cepacia).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2180928; DOI=10.1016/s0021-9258(19)39393-7;
RA   Keller J.W., Baurick K.B., Rutt G.C., O'Malley M.V., Sonafrank N.L.,
RA   Reynolds R.A., Ebbesson L.O.E., Vajdos F.F.;
RT   "Pseudomonas cepacia 2,2-dialkylglycine decarboxylase. Sequence and
RT   expression in Escherichia coli of structural and repressor genes.";
RL   J. Biol. Chem. 265:5531-5539(1990).
RN   [2]
RP   SEQUENCE REVISION.
RA   Keller J.W.;
RL   Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; J05282; AAA50843.2; -; Genomic_DNA.
DR   PIR; B35173; B35173.
DR   AlphaFoldDB; P16931; -.
DR   SMR; P16931; -.
DR   STRING; 292.DM42_5758; -.
DR   PRIDE; P16931; -.
DR   eggNOG; COG0583; Bacteria.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..294
FT                   /note="HTH-type transcriptional regulator DgdR"
FT                   /id="PRO_0000105620"
FT   DOMAIN          14..70
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        31..50
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   294 AA;  32112 MW;  3A6CD01E6DA15327 CRC64;
     MQGRKGANTL GRSLEIDLLR SFVVIAEVRA LSRAAARVGR TQSALSQQMK RLEDIVDQPL
     FQRTGRGVVL THPGERLLVH AQRILRQHDE AMADLCGTGL TGTIRFGCPD DYAEVFLPPL
     LRQFSSQHPQ AIVEIVCGPT PRLLEQLEKR AVDLAMISLP DDGANDDIIR REQLVWIGYP
     GLEPAHFDPL PLALSDPDTL DHIAACDALH RAGRDYRVAY ASSSLAGLIA LVRSGQAFAV
     MTQTAVPADL AIVNGDPRLP PLPAVGITLK FDRKRPSHLT AAFAEHIRAV LPML