ID   DGLSP_LOTGI             Reviewed;         977 AA.
AC   B3A0P1;
DT   25-JAN-2012, integrated into UniProtKB/Swiss-Prot.
DT   25-JAN-2012, sequence version 1.
DT   25-MAY-2022, entry version 16.
DE   RecName: Full=Aspartate, glycine, lysine and serine-rich protein;
DE   Flags: Fragments;
OS   Lottia gigantea (Giant owl limpet).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Patellogastropoda; Lottioidea; Lottiidae; Lottia.
OX   NCBI_TaxID=225164;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND IDENTIFICATION.
RC   TISSUE=Foot {ECO:0000269|Ref.1}, Gonad {ECO:0000269|Ref.1}, and
RC   Mantle {ECO:0000269|Ref.1};
RA   Richardson P., Lucas S., Rokhsar D., Wang M., Lindquist E.A.;
RT   "DOE Joint Genome Institute Lottia gigantea EST project.";
RL   Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   PROTEIN SEQUENCE OF 301-335; 351-373; 544-568; 573-582; 675-694; 743-766;
RP   871-886; 905-947 AND 958-965, SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RC   TISSUE=Shell;
RX   PubMed=23145877; DOI=10.1111/febs.12062;
RA   Marie B., Jackson D.J., Ramos-Silva P., Zanella-Cleon I., Guichard N.,
RA   Marin F.;
RT   "The shell-forming proteome of Lottia gigantea reveals both deep
RT   conservations and lineage-specific novelties.";
RL   FEBS J. 280:214-232(2013).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:23145877}.
CC   -!- TISSUE SPECIFICITY: Component of the acid-insoluble and acid-soluble
CC       organic matrix of calcified layers of the shell (at protein level).
CC       {ECO:0000269|PubMed:23145877}.
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DR   EMBL; FC572434; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; FC572435; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; FC624061; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; FC625878; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; FC639805; -; NOT_ANNOTATED_CDS; mRNA.
DR   AlphaFoldDB; B3A0P1; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Glycoprotein; Secreted.
FT   CHAIN           1..977
FT                   /note="Aspartate, glycine, lysine and serine-rich protein"
FT                   /id="PRO_0000415245"
FT   REGION          23..116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          246..767
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          780..922
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        33..47
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        48..63
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        252..292
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        302..346
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        462..537
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        538..555
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        574..592
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        649..681
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        684..767
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        782..805
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        828..851
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        869..894
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        136
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   NON_CONS        444..445
FT                   /evidence="ECO:0000305"
FT   NON_TER         1
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   977 AA;  96357 MW;  2D581F55DA06FE17 CRC64;
     SFYDYEFEST FEYSSEINSI VDGVLPDVDS GFPTDTEETK SEPKQPDTKP EQPSVSKPDS
     SVNGIVPGVS EPKPKQPSGS KPDGSAPGLK PGGGKPEGGI KPEPQVPITN LGSSTSQSSS
     YISITNLYDI LSIIFNLSHI GGTGKGYTDR VSGGVGIGAS GGAGGVGGAG GVGGAGGVGG
     AGGAGGADGA SVGAGGGADG GAYGGGYGAG YGGADGGADG GADGGGYGGA DGGVGAGGYG
     GAGGGAGGGD YYSDSSDSSD SDSSGSDSSE SGSSESGSYY TGYNNDGSLG DNGRGSSGHR
     YSDHGSPGNG SPDNGTPGSG SSRYTFSDDG SLAYKSQDNG TPGRKATNYR FSDDGSLAYG
     AQDNGKPGSG SPRYRYSDDG SLGNGFPDNG ASVGISPSIE SPGGPVLGSL EDELLGSDSS
     DEDDIDDGLG GLGLGAGPGG PGGFVKTPKH KPRTDKKKKP DDKPKRKPKT SRKPKTSRKP
     KTSRKPKTSR KSKTSRKTKT SRKSKRKSTR KTTRKSSRKV SRKTSRKPRR KITRRPVQRK
     QPREYKQESP EVEREHSAPS TTNVEIYRDI IKILITSLTS SRGDNGKSGD DGSGSGNGGG
     DDGNGGGAGN GGGAGNGGGA GNGGGAGNGG GNGGGGNGGG GNDNGNDNGN DDCHYDDDDE
     HRNRCEDDDD YREKCCDDDE SGGSGNFDLS SILKLMQGQS GSSSSSSATE SESSSTSTTP
     STSSLDLSAI LSTLSGRSQK TRSGSALDIS SLLGVTGSRP SVATSRGSGL DLSAVLSALG
     GGKPSTGTTV TSKPSTGTSS APGLDLSGLL GQLGPILSGL LGPKPDSKPS TGSPSTTSKP
     STGSSSGPGL DLSGLLGNLA PVLSALTGGK KPTASSKPTA PSTPSKSTGS SPGKGLDLSG
     LLGKLSPAPK PKAPKPSIGS GLLPGLDLSS ILGKLSGGKK PISGSGKGSK GSSRFCRCAL
     SCSCKSIDYG CVNIGCK