ID   DGP11_ARATH             Reviewed;         560 AA.
AC   Q9LK71; F4J2Q1;
DT   24-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   25-JAN-2012, sequence version 2.
DT   03-AUG-2022, entry version 127.
DE   RecName: Full=Putative protease Do-like 11, mitochondrial;
DE            EC=3.4.21.-;
DE   Flags: Precursor;
GN   Name=DEGP11; OrderedLocusNames=At3g16540; ORFNames=MDC8.17;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA   Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT   features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT   clones.";
RL   DNA Res. 7:217-221(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=11299370; DOI=10.1104/pp.125.4.1912;
RA   Adam Z., Adamska I., Nakabayashi K., Ostersetzer O., Haussuhl K.,
RA   Manuell A., Zheng B., Vallon O., Rodermel S.R., Shinozaki K., Clarke A.K.;
RT   "Chloroplast and mitochondrial proteases in Arabidopsis. A proposed
RT   nomenclature.";
RL   Plant Physiol. 125:1912-1918(2001).
CC   -!- FUNCTION: Putative serine protease.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion membrane {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the peptidase S1C family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB01153.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AP000373; BAB01153.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002686; AEE75833.2; -; Genomic_DNA.
DR   RefSeq; NP_001319569.1; NM_001338237.1.
DR   AlphaFoldDB; Q9LK71; -.
DR   SMR; Q9LK71; -.
DR   STRING; 3702.AT3G16540.1; -.
DR   MEROPS; S01.A01; -.
DR   PaxDb; Q9LK71; -.
DR   PRIDE; Q9LK71; -.
DR   EnsemblPlants; AT3G16540.1; AT3G16540.1; AT3G16540.
DR   GeneID; 820902; -.
DR   Gramene; AT3G16540.1; AT3G16540.1; AT3G16540.
DR   KEGG; ath:AT3G16540; -.
DR   Araport; AT3G16540; -.
DR   eggNOG; KOG1320; Eukaryota.
DR   HOGENOM; CLU_020120_10_2_1; -.
DR   InParanoid; Q9LK71; -.
DR   OMA; KISHECD; -.
DR   OrthoDB; 594175at2759; -.
DR   PRO; PR:Q9LK71; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q9LK71; baseline and differential.
DR   Genevisible; Q9LK71; AT.
DR   GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IBA:GO_Central.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.42.10; -; 1.
DR   InterPro; IPR041517; DEGP_PDZ.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR001940; Peptidase_S1C.
DR   Pfam; PF13180; PDZ_2; 1.
DR   Pfam; PF17815; PDZ_3; 2.
DR   PRINTS; PR00834; PROTEASES2C.
DR   SUPFAM; SSF50156; SSF50156; 1.
DR   SUPFAM; SSF50494; SSF50494; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Membrane; Mitochondrion; Protease; Reference proteome;
KW   Serine protease; Transit peptide.
FT   TRANSIT         1..65
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           66..560
FT                   /note="Putative protease Do-like 11, mitochondrial"
FT                   /id="PRO_0000045835"
FT   DOMAIN          288..384
FT                   /note="PDZ"
FT   REGION          117..302
FT                   /note="Serine protease"
FT   ACT_SITE        150
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        184
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        258
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   560 AA;  63695 MW;  CA0DAAE131E6EAB8 CRC64;
     MFFRPCVHTV GRYSRARVPG LLSSLFFYRS CNNVLTNSLP TVTTAGRVSR YGYICRRSST
     SAAERGVFLP FALTCRRNIH SIHEDEKKLE RWKKIEESHP LDELVLDSVV KVFSNSTEYS
     KSKPWKTLDQ KSSRGTGFAI AGRKILTNAH VVMAMNDHTF VDVKRHGSQI KYKAKVQKIS
     HECDLAILEI DSDEFWKGMN PLELGDIPPL QEVVSVVGGE NICITKGLVL RVETRIYDYS
     DSDLLSIQID ATINDENSGG PVIMGNKVVG VVYEIGFVIP TPIIKHFITS VQESRQYSCF
     GSLDLSYQSL ENVQIRNHFK MSHEMTGILI NKINSSSGAY KILRKDDIIL AIDGVPIGND
     EKVPFQNKRR IDFSYLVSMK KPGEKALVKV LRNGKEYEYN ISLKPVKPNF TVQQFYNVPS
     YYIFGGFVFV PLTKTYLDSE HHQVKISERL ADDINEGYQS LYGAQVEKVN GVEVKNLKHL
     CELIEECSTE DLRLEFKNHK VLVLNYESAK KATLQILERH KIKSVISKDI CLPMLLDDPF
     KDNKINLLPW SVLPLMFDFS