ID   DGP13_ARATH             Reviewed;         486 AA.
AC   Q9FM41; F4KHF0;
DT   24-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Putative protease Do-like 13;
DE            EC=3.4.21.-;
GN   Name=DEGP13; OrderedLocusNames=At5g40560; ORFNames=MNF13.8;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9628582; DOI=10.1093/dnares/5.1.41;
RA   Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. IV. Sequence
RT   features of the regions of 1,456,315 bp covered by nineteen physically
RT   assigned P1 and TAC clones.";
RL   DNA Res. 5:41-54(1998).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=11299370; DOI=10.1104/pp.125.4.1912;
RA   Adam Z., Adamska I., Nakabayashi K., Ostersetzer O., Haussuhl K.,
RA   Manuell A., Zheng B., Vallon O., Rodermel S.R., Shinozaki K., Clarke A.K.;
RT   "Chloroplast and mitochondrial proteases in Arabidopsis. A proposed
RT   nomenclature.";
RL   Plant Physiol. 125:1912-1918(2001).
CC   -!- FUNCTION: Putative serine protease.
CC   -!- SIMILARITY: Belongs to the peptidase S1C family. {ECO:0000305}.
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DR   EMBL; AB009052; BAB08526.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED94564.2; -; Genomic_DNA.
DR   RefSeq; NP_001318714.1; NM_001344343.1.
DR   AlphaFoldDB; Q9FM41; -.
DR   SMR; Q9FM41; -.
DR   STRING; 3702.AT5G40560.1; -.
DR   MEROPS; S01.A06; -.
DR   PaxDb; Q9FM41; -.
DR   PRIDE; Q9FM41; -.
DR   EnsemblPlants; AT5G40560.1; AT5G40560.1; AT5G40560.
DR   GeneID; 834054; -.
DR   Gramene; AT5G40560.1; AT5G40560.1; AT5G40560.
DR   KEGG; ath:AT5G40560; -.
DR   Araport; AT5G40560; -.
DR   eggNOG; KOG1320; Eukaryota.
DR   HOGENOM; CLU_020120_10_2_1; -.
DR   InParanoid; Q9FM41; -.
DR   OMA; IYNINQH; -.
DR   OrthoDB; 594175at2759; -.
DR   PhylomeDB; Q9FM41; -.
DR   PRO; PR:Q9FM41; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   Genevisible; Q9FM41; AT.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IBA:GO_Central.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.42.10; -; 1.
DR   InterPro; IPR041517; DEGP_PDZ.
DR   InterPro; IPR001478; PDZ.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR001940; Peptidase_S1C.
DR   Pfam; PF13180; PDZ_2; 1.
DR   Pfam; PF17815; PDZ_3; 1.
DR   PRINTS; PR00834; PROTEASES2C.
DR   SUPFAM; SSF50156; SSF50156; 1.
DR   SUPFAM; SSF50494; SSF50494; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Protease; Reference proteome; Serine protease.
FT   CHAIN           1..486
FT                   /note="Putative protease Do-like 13"
FT                   /id="PRO_0000093864"
FT   DOMAIN          241..334
FT                   /note="PDZ"
FT   REGION          44..229
FT                   /note="Serine protease"
FT   ACT_SITE        83
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        114
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        192
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   486 AA;  54150 MW;  8740A6560B1326F4 CRC64;
     MIQLNEPLTH VRTKPILISL EFESPGRKTI DSVATESVLN SVVKINTFSS KPNICYPWQN
     KPQKKSKGSG FVIPGKMIIT NAHVVANHIL VLVIKRGSPK KYKAEVKAIG RECDLAILVI
     ESKEFWEDMN PLELGDMPFL QESVNVIGYP TGGENISVTK GVVSRIESMD YAHGAINLPA
     IQTDAAMNPG NSGGPVCIGN KVVGVAFQTL GHSNNIGCLI PAPVVKHFIT GVEKTGQYVG
     FCSLNLSYQH MDAQTRSHFK MNSEMTGILI YNINQHSDAL NILKKYDVIL SIDGVAIEND
     GTVIIPNRER TRLDDLVSLK QLGETILLKI LREGKMHEFN ITLRPVQRLV PAGQIDNNPS
     YYIFAGFVFV PLRKQHFKGS NGEQIVVISE VLADVINVEY YMYKHLKVNS VNKVKVENLK
     HLCELIEKCC TKDLRLELGD GRVIILDYQF AKSSTSLILE RHRVPWAMSK DLMTDQSTTC
     SSTRLY