DGP14_ARATH
ID DGP14_ARATH Reviewed; 429 AA.
AC Q3E6S8; F4K4D7;
DT 24-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT 25-JAN-2012, sequence version 2.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=Putative protease Do-like 14;
DE EC=3.4.21.-;
GN Name=DEGP14; OrderedLocusNames=At5g27660; ORFNames=F15A18.120, T1G16.1;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: Putative serine protease.
CC -!- SIMILARITY: Belongs to the peptidase S1C family. {ECO:0000305}.
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DR EMBL; AC007478; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC069556; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; Q3E6S8; -.
DR SMR; Q3E6S8; -.
DR STRING; 3702.AT5G27660.1; -.
DR MEROPS; S01.A08; -.
DR PaxDb; Q3E6S8; -.
DR PeptideAtlas; Q3E6S8; -.
DR PRIDE; Q3E6S8; -.
DR Araport; AT5G27660; -.
DR eggNOG; KOG1320; Eukaryota.
DR HOGENOM; CLU_020120_2_1_1; -.
DR InParanoid; Q3E6S8; -.
DR PRO; PR:Q3E6S8; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q3E6S8; baseline and differential.
DR Genevisible; Q3E6S8; AT.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IBA:GO_Central.
DR GO; GO:0006508; P:proteolysis; IBA:GO_Central.
DR Gene3D; 2.30.42.10; -; 1.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR001940; Peptidase_S1C.
DR Pfam; PF17820; PDZ_6; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; SSF50156; 1.
DR SUPFAM; SSF50494; SSF50494; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Hydrolase; Protease; Reference proteome; Serine protease.
FT CHAIN 1..429
FT /note="Putative protease Do-like 14"
FT /id="PRO_0000093865"
FT DOMAIN 318..424
FT /note="PDZ"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00143"
FT REGION 87..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 113..338
FT /note="Serine protease"
FT COMPBIAS 99..113
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 165
FT /note="Charge relay system"
FT /evidence="ECO:0000250"
FT ACT_SITE 203
FT /note="Charge relay system"
FT /evidence="ECO:0000250"
FT ACT_SITE 281
FT /note="Charge relay system"
FT /evidence="ECO:0000250"
SQ SEQUENCE 429 AA; 45947 MW; 6EB38793CAA5CAFE CRC64;
MMNFLRRAVS SSKRSELIRI ISVATATSGI LYASTNPDAR TRVSLAIPES VRESLSLLPW
QISPGLIHRP EQSLFGNFVF SSRVSPKSEA PINDEKGVSV EASDSSSKPS NGYLGRDTIA
NAAARIGPAV VNLSVPQGFH GISMGKSIGS GTIIDADGTI LTCAHVVVDF QNIRHSSKGR
VDVTLQDGRT FEGVVVNADL QSDIALVKIK SKTPLPTAKL GFSSKLRPGD WVIAVGCPLS
LQNTVTAGIV SCVDRKSSDL GLGGKHREYL QTDCSINAGN SGGPLVNLDG EVIGVNIMKV
LAADGLGFSV PIDSVSKIIE HFKKSGRVIR PWIGLKMVEL NNLIVAQLKE RDPMFPDVER
GVLVPTVIPG SPADRAGFKP GDVVVRFDGK PVIEIMDDRV GKRMQVVVER SNKERVTLEV
IPEEANPDM
