ID   DGT1A_DEIRA             Reviewed;         373 AA.
AC   Q9RVM1;
DT   06-JUN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=Deoxyguanosinetriphosphate triphosphohydrolase-like protein 1 {ECO:0000255|HAMAP-Rule:MF_01212};
GN   OrderedLocusNames=DR_1006;
OS   Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG
OS   4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422).
OC   Bacteria; Deinococcus-Thermus; Deinococci; Deinococcales; Deinococcaceae;
OC   Deinococcus.
OX   NCBI_TaxID=243230;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB
RC   9279 / R1 / VKM B-1422;
RX   PubMed=10567266; DOI=10.1126/science.286.5444.1571;
RA   White O., Eisen J.A., Heidelberg J.F., Hickey E.K., Peterson J.D.,
RA   Dodson R.J., Haft D.H., Gwinn M.L., Nelson W.C., Richardson D.L.,
RA   Moffat K.S., Qin H., Jiang L., Pamphile W., Crosby M., Shen M.,
RA   Vamathevan J.J., Lam P., McDonald L.A., Utterback T.R., Zalewski C.,
RA   Makarova K.S., Aravind L., Daly M.J., Minton K.W., Fleischmann R.D.,
RA   Ketchum K.A., Nelson K.E., Salzberg S.L., Smith H.O., Venter J.C.,
RA   Fraser C.M.;
RT   "Genome sequence of the radioresistant bacterium Deinococcus radiodurans
RT   R1.";
RL   Science 286:1571-1577(1999).
CC   -!- SIMILARITY: Belongs to the dGTPase family. Type 2 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01212}.
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DR   EMBL; AE000513; AAF10581.1; -; Genomic_DNA.
DR   PIR; F75449; F75449.
DR   RefSeq; NP_294730.1; NC_001263.1.
DR   RefSeq; WP_010887649.1; NZ_CP015081.1.
DR   AlphaFoldDB; Q9RVM1; -.
DR   SMR; Q9RVM1; -.
DR   STRING; 243230.DR_1006; -.
DR   EnsemblBacteria; AAF10581; AAF10581; DR_1006.
DR   KEGG; dra:DR_1006; -.
DR   PATRIC; fig|243230.17.peg.1195; -.
DR   eggNOG; COG0232; Bacteria.
DR   HOGENOM; CLU_028163_1_0_0; -.
DR   InParanoid; Q9RVM1; -.
DR   OMA; KLAECGD; -.
DR   OrthoDB; 370035at2; -.
DR   Proteomes; UP000002524; Chromosome I.
DR   GO; GO:0008832; F:dGTPase activity; IBA:GO_Central.
DR   GO; GO:0006203; P:dGTP catabolic process; IBA:GO_Central.
DR   CDD; cd00077; HDc; 1.
DR   HAMAP; MF_01212; dGTPase_type2; 1.
DR   InterPro; IPR006261; dNTPase.
DR   InterPro; IPR023023; dNTPase_2.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR026875; PHydrolase_assoc_dom.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF13286; HD_assoc; 1.
DR   SMART; SM00471; HDc; 1.
DR   TIGRFAMs; TIGR01353; dGTP_triPase; 1.
DR   PROSITE; PS51831; HD; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..373
FT                   /note="Deoxyguanosinetriphosphate triphosphohydrolase-like
FT                   protein 1"
FT                   /id="PRO_0000205303"
FT   DOMAIN          76..198
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
FT   REGION          21..43
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        24..43
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   373 AA;  41373 MW;  21D0A09B9EBC6571 CRC64;
     MFTRADLEAR EAALLPPFAR RSSEARRAVP EAPSETRTAY QKDRDRVLHT KAFRRLEAKT
     QVFLNAPALG DHYRTRLTHT LEVQQVARTA ALSLGLNETL AETVALAHDL GHPPFGHAGE
     RLLDSLMRGH GETFDHNSQA RRIVTLLEER SGEQPGLNLT LDTLDGLNKH GRAALPPTQR
     QPSLEAQVVD AADALAYTAH DLDDGLRSGL LHPEDLLELP LWRELQERSG VTSQRPSSAD
     LRTLQRELLG WLIGDLTRSS DAAIAASGVA SPDAVQAHAH RLVTYSPALR GHLRGAGDFL
     RERLYRHWQV EREVYQAEQV LTELFGAFLT RPALLPPRPR SRVGRDGLPR AICDHLAGMT
     DRYALETHAA LRG