ID   DGTL1_BRUO2             Reviewed;         402 AA.
AC   A5VQ53;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Deoxyguanosinetriphosphate triphosphohydrolase-like protein {ECO:0000255|HAMAP-Rule:MF_01212};
GN   OrderedLocusNames=BOV_0867;
OS   Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=444178;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25840 / 63/290 / NCTC 10512;
RX   PubMed=19436743; DOI=10.1371/journal.pone.0005519;
RA   Tsolis R.M., Seshadri R., Santos R.L., Sangari F.J., Lobo J.M.,
RA   de Jong M.F., Ren Q., Myers G., Brinkac L.M., Nelson W.C., Deboy R.T.,
RA   Angiuoli S., Khouri H., Dimitrov G., Robinson J.R., Mulligan S.,
RA   Walker R.L., Elzer P.E., Hassan K.A., Paulsen I.T.;
RT   "Genome degradation in Brucella ovis corresponds with narrowing of its host
RT   range and tissue tropism.";
RL   PLoS ONE 4:E5519-E5519(2009).
CC   -!- SIMILARITY: Belongs to the dGTPase family. Type 2 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01212}.
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DR   EMBL; CP000708; ABQ61133.1; -; Genomic_DNA.
DR   RefSeq; WP_006012306.1; NC_009505.1.
DR   AlphaFoldDB; A5VQ53; -.
DR   SMR; A5VQ53; -.
DR   EnsemblBacteria; ABQ61133; ABQ61133; BOV_0867.
DR   GeneID; 45124302; -.
DR   KEGG; bov:BOV_0867; -.
DR   HOGENOM; CLU_028163_1_0_5; -.
DR   OMA; HCKAFRR; -.
DR   PhylomeDB; A5VQ53; -.
DR   Proteomes; UP000006383; Chromosome I.
DR   GO; GO:0016793; F:triphosphoric monoester hydrolase activity; IEA:InterPro.
DR   CDD; cd00077; HDc; 1.
DR   HAMAP; MF_01212; dGTPase_type2; 1.
DR   InterPro; IPR006261; dNTPase.
DR   InterPro; IPR023023; dNTPase_2.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR006675; HDIG_dom.
DR   InterPro; IPR026875; PHydrolase_assoc_dom.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF13286; HD_assoc; 1.
DR   SMART; SM00471; HDc; 1.
DR   TIGRFAMs; TIGR01353; dGTP_triPase; 1.
DR   TIGRFAMs; TIGR00277; HDIG; 1.
DR   PROSITE; PS51831; HD; 1.
PE   3: Inferred from homology;
KW   Hydrolase.
FT   CHAIN           1..402
FT                   /note="Deoxyguanosinetriphosphate triphosphohydrolase-like
FT                   protein"
FT                   /id="PRO_1000066415"
FT   DOMAIN          73..217
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
FT   REGION          20..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   402 AA;  45728 MW;  1E39393A2FE0A4FE CRC64;
     MSLEGIGFGY RERAPYASNP AFSRGRLVPE PESPTRTPFQ RDRDRIIHST AFRRLKHKTQ
     VFIAHEGDHY RTRLTHTIEV AQIARALARA LRLDEDLAEA VALVHDFGHT PFGHTGEDAL
     NERMENFGGF DHNAQSLRIV TKLEHRYADF DGLNLSWETL EGLVKHNGPL LGPYAAHPDI
     PVPQPILDFN ARYDLELSRF ASLEAQCAAI ADDIAYNAHD IDDGLRAGLL TLESLDEVPL
     AKRLLDIVRT RYPNLDPVRT GHELVRRQIT IMVEDVIEEA QRRLASARPG TMEDVHNQPR
     ALVGFSDAMR AEEKVLKRFL FKNLYFHESV VVRRHAADRI VQDLFDACFT DPSLMPDEWR
     LGCEALDKAA LARRVADYLA GMTDNYAVRE HRRLFDRTPD LA