ID   DGTL1_CLOP1             Reviewed;         342 AA.
AC   Q0TNV1;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Deoxyguanosinetriphosphate triphosphohydrolase-like protein {ECO:0000255|HAMAP-Rule:MF_01212};
GN   OrderedLocusNames=CPF_2266;
OS   Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB
OS   6125 / NCTC 8237 / Type A).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=195103;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / S 107 /
RC   Type A;
RX   PubMed=16825665; DOI=10.1101/gr.5238106;
RA   Myers G.S.A., Rasko D.A., Cheung J.K., Ravel J., Seshadri R., DeBoy R.T.,
RA   Ren Q., Varga J., Awad M.M., Brinkac L.M., Daugherty S.C., Haft D.H.,
RA   Dodson R.J., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A.,
RA   Khouri H., Dimitrov G.I., Watkins K.L., Mulligan S., Benton J., Radune D.,
RA   Fisher D.J., Atkins H.S., Hiscox T., Jost B.H., Billington S.J.,
RA   Songer J.G., McClane B.A., Titball R.W., Rood J.I., Melville S.B.,
RA   Paulsen I.T.;
RT   "Skewed genomic variability in strains of the toxigenic bacterial pathogen,
RT   Clostridium perfringens.";
RL   Genome Res. 16:1031-1040(2006).
CC   -!- SIMILARITY: Belongs to the dGTPase family. Type 2 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01212}.
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DR   EMBL; CP000246; ABG83625.1; -; Genomic_DNA.
DR   RefSeq; WP_011591022.1; NC_008261.1.
DR   AlphaFoldDB; Q0TNV1; -.
DR   SMR; Q0TNV1; -.
DR   STRING; 195103.CPF_2266; -.
DR   EnsemblBacteria; ABG83625; ABG83625; CPF_2266.
DR   GeneID; 29570627; -.
DR   KEGG; cpf:CPF_2266; -.
DR   eggNOG; COG0232; Bacteria.
DR   HOGENOM; CLU_028163_1_1_9; -.
DR   OMA; HCKAFRR; -.
DR   OrthoDB; 370035at2; -.
DR   Proteomes; UP000001823; Chromosome.
DR   GO; GO:0016793; F:triphosphoric monoester hydrolase activity; IEA:InterPro.
DR   CDD; cd00077; HDc; 1.
DR   HAMAP; MF_01212; dGTPase_type2; 1.
DR   InterPro; IPR023023; dNTPase_2.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR026875; PHydrolase_assoc_dom.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF13286; HD_assoc; 1.
DR   SMART; SM00471; HDc; 1.
DR   PROSITE; PS51831; HD; 1.
PE   3: Inferred from homology;
KW   Hydrolase.
FT   CHAIN           1..342
FT                   /note="Deoxyguanosinetriphosphate triphosphohydrolase-like
FT                   protein"
FT                   /id="PRO_1000138914"
FT   DOMAIN          75..190
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
SQ   SEQUENCE   342 AA;  39384 MW;  C8297F9A33B2F480 CRC64;
     MKIRENIEIF ERIKLNKVAK FSDESRGRER LEEPDEIRTC FMVDRDRIIH SKSFRRLKRK
     TQVFIRTYGD HYRTRLVHTL EVSQVARTIG VALSLNEYLI EAIALGHDLG HAAFAHIGED
     ILNDFLPGGF KHNEQSVRVA KKIEKNGLGL NLTKEVLDGI LNHSGFSNVS KVAGTFEGQV
     VRFADKIAYV NHDIDDSIRA GILKEEDLPK NIIEILGASG SERIDTLVKD CVFNTIDNID
     KGEPRVSLSN EIGDAFIQLR KFLFDNIYLG KYLEDERKKA EFVLSKVIEY YYKNWGEMPE
     LYKNICEEEG IHRGVTDYVA GMTDDYCTNE FNKIYIPKFV MY