ID   DGTL1_CLOPS             Reviewed;         342 AA.
AC   Q0SRH1;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Deoxyguanosinetriphosphate triphosphohydrolase-like protein {ECO:0000255|HAMAP-Rule:MF_01212};
GN   OrderedLocusNames=CPR_1977;
OS   Clostridium perfringens (strain SM101 / Type A).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=289380;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SM101 / Type A;
RX   PubMed=16825665; DOI=10.1101/gr.5238106;
RA   Myers G.S.A., Rasko D.A., Cheung J.K., Ravel J., Seshadri R., DeBoy R.T.,
RA   Ren Q., Varga J., Awad M.M., Brinkac L.M., Daugherty S.C., Haft D.H.,
RA   Dodson R.J., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A.,
RA   Khouri H., Dimitrov G.I., Watkins K.L., Mulligan S., Benton J., Radune D.,
RA   Fisher D.J., Atkins H.S., Hiscox T., Jost B.H., Billington S.J.,
RA   Songer J.G., McClane B.A., Titball R.W., Rood J.I., Melville S.B.,
RA   Paulsen I.T.;
RT   "Skewed genomic variability in strains of the toxigenic bacterial pathogen,
RT   Clostridium perfringens.";
RL   Genome Res. 16:1031-1040(2006).
CC   -!- SIMILARITY: Belongs to the dGTPase family. Type 2 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01212}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000312; ABG86265.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q0SRH1; -.
DR   SMR; Q0SRH1; -.
DR   EnsemblBacteria; ABG86265; ABG86265; CPR_1977.
DR   KEGG; cpr:CPR_1977; -.
DR   OMA; HCKAFRR; -.
DR   BioCyc; CPER289380:GI76-1988-MON; -.
DR   Proteomes; UP000001824; Chromosome.
DR   GO; GO:0016793; F:triphosphoric monoester hydrolase activity; IEA:InterPro.
DR   CDD; cd00077; HDc; 1.
DR   HAMAP; MF_01212; dGTPase_type2; 1.
DR   InterPro; IPR023023; dNTPase_2.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR026875; PHydrolase_assoc_dom.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF13286; HD_assoc; 1.
DR   SMART; SM00471; HDc; 1.
DR   PROSITE; PS51831; HD; 1.
PE   3: Inferred from homology;
KW   Hydrolase.
FT   CHAIN           1..342
FT                   /note="Deoxyguanosinetriphosphate triphosphohydrolase-like
FT                   protein"
FT                   /id="PRO_1000138915"
FT   DOMAIN          75..190
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
SQ   SEQUENCE   342 AA;  39397 MW;  FDA147452AC7A7E7 CRC64;
     MKIRENIENF ERIKLNKVAK FSDESVGRER LEEPDEIRTC FMVDRDRIIH SKSFRRLKRK
     TQVFIRTYGD HYRTRLVHTL EVSQVARTIG VALSLNEYLI EAIALGHDLG HAAFAHIGED
     VLNDFLPGGF KHNEQSVRVA KKIEKNGLGL NLTKEVLDGI LNHSGFSNVS KVAGTFEGQV
     VRFADKIAYV NHDIDDSIRA GILKEEDLPK NIIEILGASG SERINTLVKD CVFNTIDNID
     KGEPRVSLSK EIGDAFVQLR KFLFDNIYLG KYLEDERKKA EFILEKVIEY YYNNWGEMPE
     LYRNICEEEG IHRGVTDYIA GMTDDYCTNE FNKIYIPKFV MY