ID   DGTL1_CLOTE             Reviewed;         349 AA.
AC   Q892S8;
DT   20-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   20-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Deoxyguanosinetriphosphate triphosphohydrolase-like protein {ECO:0000255|HAMAP-Rule:MF_01212};
GN   OrderedLocusNames=CTC_02012;
OS   Clostridium tetani (strain Massachusetts / E88).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=212717;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Massachusetts / E88;
RX   PubMed=12552129; DOI=10.1073/pnas.0335853100;
RA   Brueggemann H., Baeumer S., Fricke W.F., Wiezer A., Liesegang H.,
RA   Decker I., Herzberg C., Martinez-Arias R., Merkl R., Henne A.,
RA   Gottschalk G.;
RT   "The genome sequence of Clostridium tetani, the causative agent of tetanus
RT   disease.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:1316-1321(2003).
CC   -!- SIMILARITY: Belongs to the dGTPase family. Type 2 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01212}.
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DR   EMBL; AE015927; AAO36516.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q892S8; -.
DR   SMR; Q892S8; -.
DR   STRING; 212717.CTC_02012; -.
DR   PRIDE; Q892S8; -.
DR   EnsemblBacteria; AAO36516; AAO36516; CTC_02012.
DR   KEGG; ctc:CTC_02012; -.
DR   HOGENOM; CLU_028163_1_1_9; -.
DR   OMA; HCKAFRR; -.
DR   Proteomes; UP000001412; Chromosome.
DR   GO; GO:0016793; F:triphosphoric monoester hydrolase activity; IEA:InterPro.
DR   CDD; cd00077; HDc; 1.
DR   HAMAP; MF_01212; dGTPase_type2; 1.
DR   InterPro; IPR006261; dNTPase.
DR   InterPro; IPR023023; dNTPase_2.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR026875; PHydrolase_assoc_dom.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF13286; HD_assoc; 1.
DR   SMART; SM00471; HDc; 1.
DR   TIGRFAMs; TIGR01353; dGTP_triPase; 1.
DR   PROSITE; PS51831; HD; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..349
FT                   /note="Deoxyguanosinetriphosphate triphosphohydrolase-like
FT                   protein"
FT                   /id="PRO_0000205300"
FT   DOMAIN          80..197
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
SQ   SEQUENCE   349 AA;  40167 MW;  CEBCDDE2475DEE31 CRC64;
     MSIDKMSLRK RVENIERISI IPEGTKSEDT KGRIIKENQD DIRTVFMVDR DRIIHSKSFR
     RLKHKTQVYI KTWGDHYRTR LTHTLEVAQI GKTIGKSIGL NEDLIEAIAL GHDIGHVAFA
     HSGEEVLNEL LPNGFKHNIN SIRVLTKIEK QGKGLNLTKE VLDGILHHSG FSNKKDITKA
     FTLEGQVVKY SDKIAYVNHD IDDSIRAGLL HESDLPKDLI NVLGRNHSDR IDTLVKDCIN
     KTLENIKLGT IEVGMSEKIE IALKELRKFM FQRVYKGSIL KEERDKAKFV LYQVFNYYLK
     NSNKMPEFYK NIVEQEGLYQ GVADYISGMS DDYCLLLFNN IYVPKIVIY