ID   DGTL1_HISS2             Reviewed;         450 AA.
AC   B0UUG0;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Deoxyguanosinetriphosphate triphosphohydrolase-like protein {ECO:0000255|HAMAP-Rule:MF_01212};
GN   OrderedLocusNames=HSM_1439;
OS   Histophilus somni (strain 2336) (Haemophilus somnus).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Histophilus.
OX   NCBI_TaxID=228400;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2336;
RG   US DOE Joint Genome Institute;
RA   Siddaramappa S., Duncan A.J., Challacombe J.F., Rainey D., Gillaspy A.F.,
RA   Carson M., Gipson J., Gipson M., Bruce D., Detter J.C., Han C.S., Land M.,
RA   Tapia R., Thompson L.S., Orvis J., Zaitshik J., Barnes G., Brettin T.S.,
RA   Dyer D.W., Inzana T.J.;
RT   "Complete sequence of Haemophilus somnus 2336.";
RL   Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the dGTPase family. Type 2 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01212}.
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DR   EMBL; CP000947; ACA31184.1; -; Genomic_DNA.
DR   RefSeq; WP_012340581.1; NC_010519.1.
DR   AlphaFoldDB; B0UUG0; -.
DR   SMR; B0UUG0; -.
DR   STRING; 228400.HSM_1439; -.
DR   EnsemblBacteria; ACA31184; ACA31184; HSM_1439.
DR   KEGG; hsm:HSM_1439; -.
DR   HOGENOM; CLU_028163_0_0_6; -.
DR   OMA; KLAECGD; -.
DR   OrthoDB; 370035at2; -.
DR   GO; GO:0008832; F:dGTPase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0006203; P:dGTP catabolic process; IEA:InterPro.
DR   CDD; cd00077; HDc; 1.
DR   HAMAP; MF_01212; dGTPase_type2; 1.
DR   InterPro; IPR006261; dNTPase.
DR   InterPro; IPR020779; dNTPase_1.
DR   InterPro; IPR023023; dNTPase_2.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR026875; PHydrolase_assoc_dom.
DR   PANTHER; PTHR11373:SF32; PTHR11373:SF32; 1.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF13286; HD_assoc; 1.
DR   SMART; SM00471; HDc; 1.
DR   TIGRFAMs; TIGR01353; dGTP_triPase; 1.
DR   PROSITE; PS51831; HD; 1.
PE   3: Inferred from homology;
KW   Hydrolase.
FT   CHAIN           1..450
FT                   /note="Deoxyguanosinetriphosphate triphosphohydrolase-like
FT                   protein"
FT                   /id="PRO_1000138921"
FT   DOMAIN          61..274
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
SQ   SEQUENCE   450 AA;  52437 MW;  70FE5437A56190BD CRC64;
     MKLQINSSWQ ERFLADPPRE KDHRPPFRRD RGRILHSAAF RCLQAKTQIH AIGENDFYRT
     RLTHSLEVAQ IGSSIVAQMK LIDSFISLAQ QLKEDRAELQ KQLKLILPSN DLIESLCFAH
     DIGHPPFGHG GEVALNYMMR HHGGFEGNAQ TFRLLTKLEP YTPNAGMNLT RRTLLGVVKY
     PTILDRSSPQ YHQGVIVDNV DSKYVKISAW KPGKGIFRDD LKMFEWLLEP LSENDRTLFG
     QYKKERTRPD EVLKTRYKSL DCSIMELADD IAYAVHDLED AIVVGVVTFQ QWQSAVEKLT
     ECRSEWIVEN VQSLSQKLFS ELHYERKNAI GALVNYFITH VRWKINNGFS EPLLRYNAEL
     PDEVIEVLTI FKHFVWEYVI KHVDTQRVEY KGQRMLTEMF QIFDSDPLRL LPRNTAMRWQ
     KATETDRKRI ICDYIAGMSD AYALRVYQQL