ID   DGTL1_MYCA1             Reviewed;         423 AA.
AC   A0QEC2;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Deoxyguanosinetriphosphate triphosphohydrolase-like protein {ECO:0000255|HAMAP-Rule:MF_01212};
GN   OrderedLocusNames=MAV_2042;
OS   Mycobacterium avium (strain 104).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=243243;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=104;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the dGTPase family. Type 2 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01212}.
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DR   EMBL; CP000479; ABK67384.1; -; Genomic_DNA.
DR   RefSeq; WP_003872507.1; NC_008595.1.
DR   AlphaFoldDB; A0QEC2; -.
DR   SMR; A0QEC2; -.
DR   EnsemblBacteria; ABK67384; ABK67384; MAV_2042.
DR   GeneID; 66693520; -.
DR   KEGG; mav:MAV_2042; -.
DR   HOGENOM; CLU_028163_0_1_11; -.
DR   OMA; FGVYEDD; -.
DR   OrthoDB; 370035at2; -.
DR   Proteomes; UP000001574; Chromosome.
DR   GO; GO:0008832; F:dGTPase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0006203; P:dGTP catabolic process; IEA:InterPro.
DR   CDD; cd00077; HDc; 1.
DR   HAMAP; MF_01212; dGTPase_type2; 1.
DR   InterPro; IPR006261; dNTPase.
DR   InterPro; IPR020779; dNTPase_1.
DR   InterPro; IPR023023; dNTPase_2.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR026875; PHydrolase_assoc_dom.
DR   PANTHER; PTHR11373:SF32; PTHR11373:SF32; 1.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF13286; HD_assoc; 1.
DR   SMART; SM00471; HDc; 1.
DR   TIGRFAMs; TIGR01353; dGTP_triPase; 1.
DR   PROSITE; PS51831; HD; 1.
PE   3: Inferred from homology;
KW   Hydrolase.
FT   CHAIN           1..423
FT                   /note="Deoxyguanosinetriphosphate triphosphohydrolase-like
FT                   protein"
FT                   /id="PRO_1000066420"
FT   DOMAIN          72..220
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
FT   REGION          1..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..20
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   423 AA;  45770 MW;  B1487E910867CE84 CRC64;
     MTRNQHDPYD DFDRQRRVAE APKTAGLPGT EGQHRTDFAR DRARVLHSAA LRRLADKTQV
     VGPREGDTPR TRLTHSLEVA QIGRGMAVGL GCDLDLVELA GLAHDIGHPP YGHNGERALD
     EVAAAYGGFE GNAQNFRILT SLEPKVLDAQ GNSAGLNLTR ASLDAVIKYP WRRGEGPGTS
     KFGFYDDDRE AAAWVRAGAP AGRMCLEAQV MDWADDVAYS VHDVEDGVVS QRIDLRVLAD
     DDEAAALAKL GESEFSRVGA DDFMAAARRL SALPVVAAVG KYDATLASSV ALKRLTSELV
     GRFASAAIAT TRAAAGPGPL VRYRAELAVP DLVRAEVALL KILALQFIMS DPRHQQTQAG
     QRERIHRVAH WLYAGAPRTL DPVFAAAFNT AADDGARWRV IVDQIASYTE GRLERIDARQ
     AGP