ID   DGTL1_RICAE             Reviewed;         384 AA.
AC   C3PMA3;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2009, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Deoxyguanosinetriphosphate triphosphohydrolase-like protein {ECO:0000255|HAMAP-Rule:MF_01212};
GN   OrderedLocusNames=RAF_ORF0088;
OS   Rickettsia africae (strain ESF-5).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=347255;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ESF-5;
RX   PubMed=19379498; DOI=10.1186/1471-2164-10-166;
RA   Fournier P.-E., El Karkouri K., Leroy Q., Robert C., Giumelli B.,
RA   Renesto P., Socolovschi C., Parola P., Audic S., Raoult D.;
RT   "Analysis of the Rickettsia africae genome reveals that virulence
RT   acquisition in Rickettsia species may be explained by genome reduction.";
RL   BMC Genomics 10:166-166(2009).
CC   -!- SIMILARITY: Belongs to the dGTPase family. Type 2 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01212}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP001612; ACP53063.1; -; Genomic_DNA.
DR   RefSeq; WP_010976778.1; NC_012633.1.
DR   AlphaFoldDB; C3PMA3; -.
DR   SMR; C3PMA3; -.
DR   EnsemblBacteria; ACP53063; ACP53063; RAF_ORF0088.
DR   KEGG; raf:RAF_ORF0088; -.
DR   HOGENOM; CLU_028163_1_0_5; -.
DR   OMA; HCKAFRR; -.
DR   Proteomes; UP000002305; Chromosome.
DR   GO; GO:0016793; F:triphosphoric monoester hydrolase activity; IEA:InterPro.
DR   CDD; cd00077; HDc; 1.
DR   HAMAP; MF_01212; dGTPase_type2; 1.
DR   InterPro; IPR006261; dNTPase.
DR   InterPro; IPR023023; dNTPase_2.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR026875; PHydrolase_assoc_dom.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF13286; HD_assoc; 1.
DR   SMART; SM00471; HDc; 1.
DR   TIGRFAMs; TIGR01353; dGTP_triPase; 1.
DR   PROSITE; PS51831; HD; 1.
PE   3: Inferred from homology;
KW   Hydrolase.
FT   CHAIN           1..384
FT                   /note="Deoxyguanosinetriphosphate triphosphohydrolase-like
FT                   protein"
FT                   /id="PRO_1000213889"
FT   DOMAIN          62..198
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
SQ   SEQUENCE   384 AA;  44293 MW;  6C0F3E9734E8F933 CRC64;
     MLASYASDPL KSRGRLYKEI PTSYRNEFER DRDRIIHTNA FRRLQYKTQV FINHEGDHYR
     NRLTHSLEVS TVARSVASTL NLSNDLAETI ALAHDLGHTP FGHAGERALN ECMREYNGFS
     HNAQSLKILT LLEKRYAAYN GVNLTWEVLE GIVKHNGPIL GEINEYIAEY NKQNDLELST
     YASAEAQIAA LADDISYISH DLEDSIGAKI IDFHSLAELK YIDQHVVELK SKFKNISSSC
     LIYEVVRKLI HELITDLLWQ TKENLNKEKI TNIDEIRNLN YQIVDFTEKT NKNIKETKKF
     LHERVYKSNK ITAISLKCTK IVQGLFKVYM DDINLLPVNW KMLIDSNETY SKARVVADYI
     AGMTDRFAIQ EYNQLCSTSY ITCF