ID   DGTL1_RICTY             Reviewed;         384 AA.
AC   Q68XT8;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Deoxyguanosinetriphosphate triphosphohydrolase-like protein {ECO:0000255|HAMAP-Rule:MF_01212};
GN   OrderedLocusNames=RT0068;
OS   Rickettsia typhi (strain ATCC VR-144 / Wilmington).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=257363;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-144 / Wilmington;
RX   PubMed=15317790; DOI=10.1128/jb.186.17.5842-5855.2004;
RA   McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E.,
RA   McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E.,
RA   Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A., Hong C.,
RA   Yu X.-J., Walker D.H., Weinstock G.M.;
RT   "Complete genome sequence of Rickettsia typhi and comparison with sequences
RT   of other Rickettsiae.";
RL   J. Bacteriol. 186:5842-5855(2004).
CC   -!- SIMILARITY: Belongs to the dGTPase family. Type 2 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01212}.
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DR   EMBL; AE017197; AAU03554.1; -; Genomic_DNA.
DR   RefSeq; WP_011190541.1; NC_006142.1.
DR   AlphaFoldDB; Q68XT8; -.
DR   SMR; Q68XT8; -.
DR   STRING; 257363.RT0068; -.
DR   EnsemblBacteria; AAU03554; AAU03554; RT0068.
DR   KEGG; rty:RT0068; -.
DR   eggNOG; COG0232; Bacteria.
DR   HOGENOM; CLU_028163_1_0_5; -.
DR   OMA; HCKAFRR; -.
DR   OrthoDB; 370035at2; -.
DR   Proteomes; UP000000604; Chromosome.
DR   GO; GO:0016793; F:triphosphoric monoester hydrolase activity; IEA:InterPro.
DR   CDD; cd00077; HDc; 1.
DR   HAMAP; MF_01212; dGTPase_type2; 1.
DR   InterPro; IPR006261; dNTPase.
DR   InterPro; IPR023023; dNTPase_2.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR026875; PHydrolase_assoc_dom.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF13286; HD_assoc; 1.
DR   SMART; SM00471; HDc; 1.
DR   TIGRFAMs; TIGR01353; dGTP_triPase; 1.
DR   PROSITE; PS51831; HD; 1.
PE   3: Inferred from homology;
KW   Hydrolase.
FT   CHAIN           1..384
FT                   /note="Deoxyguanosinetriphosphate triphosphohydrolase-like
FT                   protein"
FT                   /id="PRO_0000272409"
FT   DOMAIN          63..199
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
SQ   SEQUENCE   384 AA;  44516 MW;  A6F239F9E5A58146 CRC64;
     MLASYASDPL KSRGRLYKEI PTYYRNEFER DRDRIIHTNA FRRLQYKTQV FINHEEGDHY
     RNRLTHSLEV ATVARSVANT LNLSSDLAET IALAHDLGHT PFGHVGEKAL NECMKEYNGF
     SHNSQSLKIL TLLEKRYAAY NGVNLTWEVL EGIVKHNGPI LGAINEYVAE YNKQNDLELN
     TYASAEAQIA SLADDISYIS HDLEDSIIAK IIDFNNLAEL QYIDNYVFKL KSKFKDISPS
     CLIYEIVRKL IHELITDLLL QTKENLKKEK ITNINEIRNL HYQIVDFTEK TNERINETKK
     FLHKRVYESN KMIAISIKCT KIVQGLFKIY MDDINLLPTN WKILIDSNET YSKARVIADY
     IAGMTDRFAI QEYNQLCAPK FNKI