ID   DGTL1_THIDA             Reviewed;         376 AA.
AC   Q3SLY3;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Deoxyguanosinetriphosphate triphosphohydrolase-like protein {ECO:0000255|HAMAP-Rule:MF_01212};
GN   OrderedLocusNames=Tbd_0316;
OS   Thiobacillus denitrificans (strain ATCC 25259).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Thiobacillaceae; Thiobacillus.
OX   NCBI_TaxID=292415;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25259;
RX   PubMed=16452431; DOI=10.1128/jb.188.4.1473-1488.2006;
RA   Beller H.R., Chain P.S., Letain T.E., Chakicherla A., Larimer F.W.,
RA   Richardson P.M., Coleman M.A., Wood A.P., Kelly D.P.;
RT   "The genome sequence of the obligately chemolithoautotrophic, facultatively
RT   anaerobic bacterium Thiobacillus denitrificans.";
RL   J. Bacteriol. 188:1473-1488(2006).
CC   -!- SIMILARITY: Belongs to the dGTPase family. Type 2 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01212}.
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DR   EMBL; CP000116; AAZ96269.1; -; Genomic_DNA.
DR   RefSeq; WP_011310829.1; NC_007404.1.
DR   AlphaFoldDB; Q3SLY3; -.
DR   SMR; Q3SLY3; -.
DR   STRING; 292415.Tbd_0316; -.
DR   EnsemblBacteria; AAZ96269; AAZ96269; Tbd_0316.
DR   KEGG; tbd:Tbd_0316; -.
DR   eggNOG; COG0232; Bacteria.
DR   HOGENOM; CLU_028163_1_0_4; -.
DR   OMA; HCKAFRR; -.
DR   OrthoDB; 370035at2; -.
DR   Proteomes; UP000008291; Chromosome.
DR   GO; GO:0016793; F:triphosphoric monoester hydrolase activity; IEA:InterPro.
DR   CDD; cd00077; HDc; 1.
DR   HAMAP; MF_01212; dGTPase_type2; 1.
DR   InterPro; IPR006261; dNTPase.
DR   InterPro; IPR023023; dNTPase_2.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR026875; PHydrolase_assoc_dom.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF13286; HD_assoc; 1.
DR   SMART; SM00471; HDc; 1.
DR   TIGRFAMs; TIGR01353; dGTP_triPase; 1.
DR   PROSITE; PS51831; HD; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..376
FT                   /note="Deoxyguanosinetriphosphate triphosphohydrolase-like
FT                   protein"
FT                   /id="PRO_1000066443"
FT   DOMAIN          65..196
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        15..32
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   376 AA;  42726 MW;  348F3365A9A5EC4C CRC64;
     MEPSFAPYAA HSSQTRGRVH REAPAAPRSE FQRDRDRIIH STAFRRLEYK TQVFVNHEGD
     LFRTRLTHSI EVAQIGRTIA RLLNLNEDLV EAVALAHDLG HTPFGHAGQD ALNACMREHG
     GFEHNLQSLR VVDLLEERYA EFDGLNLTFE AREGILKHCA LSNAEKLGEV GRRFIDKKQP
     SLEAQVANLA DEIAYNNHDV DDGLRSGLIT LEQLSEVTIF GRHLAEVRRK HPTLQGRRVV
     TETVRRIINA LILDLVDTTR TNVVNSGVET LDDVRNAPPL AAFSPAILEQ HRELKRFLLH
     HLYRHYKVAR MSTKAGRIIS DLYAAFTGDA RLLPPEHQAR ESLEGTRAVA DYIAGMTDRY
     AMREHRRIYA VEEIYD