ID   DGTL1_VIBC3             Reviewed;         441 AA.
AC   A5F6T5; C3M231;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Deoxyguanosinetriphosphate triphosphohydrolase-like protein {ECO:0000255|HAMAP-Rule:MF_01212};
GN   Name=dgt; OrderedLocusNames=VC0395_A1566, VC395_2094;
OS   Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 /
OS   O395).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=345073;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RA   Heidelberg J.;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RX   PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA   Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA   Wang W., Wang J., Qian W., Li D., Wang L.;
RT   "A recalibrated molecular clock and independent origins for the cholera
RT   pandemic clones.";
RL   PLoS ONE 3:E4053-E4053(2008).
CC   -!- SIMILARITY: Belongs to the dGTPase family. Type 2 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01212}.
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DR   EMBL; CP000627; ABQ20158.1; -; Genomic_DNA.
DR   EMBL; CP001235; ACP10086.1; -; Genomic_DNA.
DR   RefSeq; WP_001198175.1; NZ_JAACZH010000001.1.
DR   AlphaFoldDB; A5F6T5; -.
DR   SMR; A5F6T5; -.
DR   STRING; 345073.VC395_2094; -.
DR   EnsemblBacteria; ABQ20158; ABQ20158; VC0395_A1566.
DR   KEGG; vco:VC0395_A1566; -.
DR   KEGG; vcr:VC395_2094; -.
DR   PATRIC; fig|345073.21.peg.2022; -.
DR   eggNOG; COG0232; Bacteria.
DR   HOGENOM; CLU_028163_0_0_6; -.
DR   OMA; KLAECGD; -.
DR   Proteomes; UP000000249; Chromosome 2.
DR   GO; GO:0008832; F:dGTPase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0006203; P:dGTP catabolic process; IEA:InterPro.
DR   CDD; cd00077; HDc; 1.
DR   HAMAP; MF_01212; dGTPase_type2; 1.
DR   InterPro; IPR006261; dNTPase.
DR   InterPro; IPR020779; dNTPase_1.
DR   InterPro; IPR023023; dNTPase_2.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR026875; PHydrolase_assoc_dom.
DR   PANTHER; PTHR11373:SF32; PTHR11373:SF32; 1.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF13286; HD_assoc; 1.
DR   SMART; SM00471; HDc; 1.
DR   TIGRFAMs; TIGR01353; dGTP_triPase; 1.
DR   PROSITE; PS51831; HD; 1.
PE   3: Inferred from homology;
KW   Hydrolase.
FT   CHAIN           1..441
FT                   /note="Deoxyguanosinetriphosphate triphosphohydrolase-like
FT                   protein"
FT                   /id="PRO_1000138938"
FT   DOMAIN          62..255
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
SQ   SEQUENCE   441 AA;  49897 MW;  0695B0391C8F401C CRC64;
     MQVSLNPEWL ARNNDEHKIR RNDHRSPFQR DRARILHSAA FRRLQAKTQV HGTSLNDFHR
     TRLTHSLEAA QIGTGIVAQI KLKQPEFREL LPSDSLIDSL CLAHDIGHPP YGHGGEIALN
     YMMRDHGGFE GNAQTFRIVT SLEPYTEHHG MNLSRRTLLG LLKYPALLSA TRAAIPPPAV
     AHQRQLKAKD WSPAKGIYDC DLASLDWVLE PLCESDRELL GQMRAEPSSP KEHRKTRFKS
     LDCSIMELAD DIAYGVHDLE DAIVLGMVTR AQWQEAAAAQ LAECGDPWFE EHIAELSEML
     FSGKHYVCKD AIGGIVNALL TSISVKPVEA PFHNELLAFN AYIEPHMGNA LEVLKHFVSQ
     YVIQIPQVQR FEYKGQQLIM DLFEALSADP ERLLPQATGE KWRKAQEQDE GMRVICDYIA
     AMTDAYAQRL HQQLFSAQSH Y