ID   DGTL1_VIBPA             Reviewed;         440 AA.
AC   Q87R73;
DT   20-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   20-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Deoxyguanosinetriphosphate triphosphohydrolase-like protein {ECO:0000255|HAMAP-Rule:MF_01212};
GN   OrderedLocusNames=VP0925;
OS   Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=223926;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RIMD 2210633;
RX   PubMed=12620739; DOI=10.1016/s0140-6736(03)12659-1;
RA   Makino K., Oshima K., Kurokawa K., Yokoyama K., Uda T., Tagomori K.,
RA   Iijima Y., Najima M., Nakano M., Yamashita A., Kubota Y., Kimura S.,
RA   Yasunaga T., Honda T., Shinagawa H., Hattori M., Iida T.;
RT   "Genome sequence of Vibrio parahaemolyticus: a pathogenic mechanism
RT   distinct from that of V. cholerae.";
RL   Lancet 361:743-749(2003).
CC   -!- SIMILARITY: Belongs to the dGTPase family. Type 2 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01212}.
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DR   EMBL; BA000031; BAC59188.1; -; Genomic_DNA.
DR   RefSeq; NP_797304.1; NC_004603.1.
DR   RefSeq; WP_005482541.1; NC_004603.1.
DR   AlphaFoldDB; Q87R73; -.
DR   SMR; Q87R73; -.
DR   STRING; 223926.28805912; -.
DR   EnsemblBacteria; BAC59188; BAC59188; BAC59188.
DR   KEGG; vpa:VP0925; -.
DR   PATRIC; fig|223926.6.peg.877; -.
DR   eggNOG; COG0232; Bacteria.
DR   HOGENOM; CLU_028163_0_0_6; -.
DR   OMA; KLAECGD; -.
DR   Proteomes; UP000002493; Chromosome 1.
DR   GO; GO:0008832; F:dGTPase activity; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0006203; P:dGTP catabolic process; IEA:InterPro.
DR   HAMAP; MF_01212; dGTPase_type2; 1.
DR   InterPro; IPR006261; dNTPase.
DR   InterPro; IPR020779; dNTPase_1.
DR   InterPro; IPR023023; dNTPase_2.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR026875; PHydrolase_assoc_dom.
DR   PANTHER; PTHR11373:SF32; PTHR11373:SF32; 1.
DR   Pfam; PF01966; HD; 1.
DR   Pfam; PF13286; HD_assoc; 1.
DR   SMART; SM00471; HDc; 1.
DR   TIGRFAMs; TIGR01353; dGTP_triPase; 1.
DR   PROSITE; PS51831; HD; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..440
FT                   /note="Deoxyguanosinetriphosphate triphosphohydrolase-like
FT                   protein"
FT                   /id="PRO_0000205324"
FT   DOMAIN          62..255
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
SQ   SEQUENCE   440 AA;  50081 MW;  CB9E5C79B3066D73 CRC64;
     MSFELHSLWQ ERHDDEHKIR RDDHRSPYQR DRARILHSAA FRRLQAKTQV HGNSLEDFHR
     SRLTHSLEAA QLGTGIVAQL KKKQSEFKEL LPSDSLIDSL CLAHDIGHPP YGHGGEVALN
     YMMRDHGGFE GNAQTFRIVT KLEPYTEHFG MNLSRRTLLG LIKYPALISQ TRSVKLPNPA
     EHQRRLKAKE WSPAKGIYDC DKDLFDWVIA PLSENDKSLL SQMRYRPDSD LEHSKTRFKS
     LDCSIMELAD DIAYGVHDLE DAIVLGMVTR QQWQEGAASQ LADCGDPWFE EHIGSIGQML
     FSGKHHQRKD AIGGMVNALL TSISIKVVDE PFQNPLLAWN ACLEPHMAKA LDVLKHFVSQ
     YVIQVPQVQI VEYKGQQIIM DIFEALSADP ERLLPIHTKE LWQSATSDSG KMRVIADYIS
     AMTDGHAQKL HRQLFSSIVL