ID   DHAR_MYCSX              Reviewed;         198 AA.
AC   Q9RAJ1;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=HTH-type transcriptional repressor DhaR;
GN   Name=dhaR;
OS   Mycobacterium sp. (strain GP1).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; unclassified Mycobacterium.
OX   NCBI_TaxID=106323;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10735862; DOI=10.1128/jb.182.8.2191-2199.2000;
RA   Poelarends G.J., Kulakov L.A., Larkin M.J., van Hylckama Vlieg J.E.T.,
RA   Janssen D.B.;
RT   "Roles of horizontal gene transfer and gene integration in evolution of
RT   1,3-dichloropropene- and 1,2-dibromoethane-degradative pathways.";
RL   J. Bacteriol. 182:2191-2199(2000).
CC   -!- FUNCTION: Transcriptional repressor for the dhaA haloalkane
CC       dehalogenase gene.
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DR   EMBL; AJ250372; CAB65288.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9RAJ1; -.
DR   SMR; Q9RAJ1; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProt.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR   InterPro; IPR011075; TetR_C.
DR   Pfam; PF16925; TetR_C_13; 1.
DR   Pfam; PF00440; TetR_N; 1.
DR   PRINTS; PR00455; HTHTETR.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF48498; SSF48498; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   4: Predicted;
KW   DNA-binding; Repressor; Transcription; Transcription regulation.
FT   CHAIN           1..198
FT                   /note="HTH-type transcriptional repressor DhaR"
FT                   /id="PRO_0000070595"
FT   DOMAIN          4..64
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
SQ   SEQUENCE   198 AA;  22239 MW;  48FBEA5A261EBB17 CRC64;
     MARTPVRQHL VEKGTQVFLE RGYSGSAVQD ITAAAEVPKG SFYNHFESKE AFGGQVLQEF
     FSDLQRTISS TLEDASVPPV RRLQNYFAAI IETLDGQGCL IGNFSVELSP LSDVVRTELL
     RIFEQWVKPF QKCIIEGQET GSIRRDLAPD LLADFLIASW QGAILRMKIE RNREPLDQFL
     TVVFEALLPS TENISNES