ID   DHGP_ASPNG              Reviewed;          99 AA.
AC   P55804;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   10-FEB-2021, entry version 68.
DE   RecName: Full=NADP(+)-dependent glycerol dehydrogenase;
DE            EC=1.1.1.72;
DE   Flags: Fragments;
OS   Aspergillus niger.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=5061;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=9038161; DOI=10.1074/jbc.272.9.5544;
RA   Norbeck J., Blomberg A.;
RT   "Metabolic and regulatory changes associated with growth of Saccharomyces
RT   cerevisiae in 1.4 M NaCl. Evidence for osmotic induction of glycerol
RT   dissimilation via the dihydroxyacetone pathway.";
RL   J. Biol. Chem. 272:5544-5554(1997).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=glycerol + NADP(+) = D-glyceraldehyde + H(+) + NADPH;
CC         Xref=Rhea:RHEA:23592, ChEBI:CHEBI:15378, ChEBI:CHEBI:17378,
CC         ChEBI:CHEBI:17754, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349; EC=1.1.1.72;
CC   -!- SIMILARITY: Belongs to the aldo/keto reductase family. {ECO:0000305}.
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DR   GO; GO:0047956; F:glycerol dehydrogenase [NADP+] activity; IEA:UniProtKB-EC.
DR   InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR   SUPFAM; SSF51430; SSF51430; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; NADP; Oxidoreductase.
FT   CHAIN           <1..>99
FT                   /note="NADP(+)-dependent glycerol dehydrogenase"
FT                   /id="PRO_0000124676"
FT   NON_CONS        19..20
FT                   /evidence="ECO:0000305"
FT   NON_CONS        38..39
FT                   /evidence="ECO:0000305"
FT   NON_CONS        52..53
FT                   /evidence="ECO:0000305"
FT   NON_CONS        64..65
FT                   /evidence="ECO:0000305"
FT   NON_CONS        70..71
FT                   /evidence="ECO:0000305"
FT   NON_CONS        85..86
FT                   /evidence="ECO:0000305"
FT   NON_TER         1
FT   NON_TER         99
SQ   SEQUENCE   99 AA;  10672 MW;  4BC9A366B8F75332 CRC64;
     IPGVGFGTFA NEGATGXTYL KVDYIDLFLV HWPIAAEKAI GVSNWTIEGL EKENILPEAY
     SPLGIESNFK XGGYTLAQVL IAXGLSIQLT DXXYXAVNK