ID   DHM2_METSP              Reviewed;          18 AA.
AC   Q09053;
DT   10-JAN-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Methanol dehydrogenase [cytochrome c] subunit 2;
DE            EC=1.1.2.7;
DE   AltName: Full=MDH small subunit beta;
DE   Flags: Fragment;
GN   Name=moxI {ECO:0000303|PubMed:7685335};
OS   Methylomonas sp.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Methylococcales;
OC   Methylococcaceae; Methylomonas.
OX   NCBI_TaxID=418;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, AND SUBUNIT.
RC   STRAIN=A4 {ECO:0000269|PubMed:7685335};
RX   PubMed=7685335; DOI=10.1128/jb.175.12.3767-3775.1993;
RA   Waechter-Brulla D., DiSpirito A.A., Chistoserdova L.V., Lidstrom M.E.;
RT   "Methanol oxidation genes in the marine methanotroph Methylomonas sp.
RT   strain A4.";
RL   J. Bacteriol. 175:3767-3775(1993).
CC   -!- FUNCTION: Catalyzes the oxidation of primary alcohols including
CC       methanol. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a primary alcohol + 2 Fe(III)-[cytochrome cL] = an aldehyde +
CC         2 Fe(II)-[cytochrome cL] + 2 H(+); Xref=Rhea:RHEA:51004, Rhea:RHEA-
CC         COMP:12863, Rhea:RHEA-COMP:12864, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:15734, ChEBI:CHEBI:17478, ChEBI:CHEBI:29033,
CC         ChEBI:CHEBI:29034; EC=1.1.2.7;
CC   -!- SUBUNIT: Heterotetramer composed of 2 alpha and 2 beta subunits.
CC       {ECO:0000269|PubMed:7685335}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the methanol dehydrogenase subunit 2 family.
CC       {ECO:0000255}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; Q09053; -.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0052933; F:alcohol dehydrogenase (cytochrome c(L)) activity; IEA:UniProtKB-EC.
DR   GO; GO:0004022; F:alcohol dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0015946; P:methanol oxidation; IEA:InterPro.
DR   Gene3D; 4.10.160.10; -; 1.
DR   InterPro; IPR003420; Meth_DH_bsu.
DR   InterPro; IPR036557; Meth_DH_bsu_sf.
DR   Pfam; PF02315; MDH; 1.
DR   SUPFAM; SSF48666; SSF48666; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Methanol utilization;
KW   Oxidoreductase; Periplasm.
FT   CHAIN           1..>18
FT                   /note="Methanol dehydrogenase [cytochrome c] subunit 2"
FT                   /id="PRO_0000205343"
FT   DISULFID        6..11
FT                   /evidence="ECO:0000250|UniProtKB:P14775"
FT   NON_TER         18
FT                   /evidence="ECO:0000303|PubMed:7685335"
SQ   SEQUENCE   18 AA;  2014 MW;  2B0412DBD2B8B52D CRC64;
     YDGTNCKPGV CWEPKPGY