ID   DHQSH_PERMH             Reviewed;         331 AA.
AC   C0QRE8;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=3-dehydroquinate synthase homolog {ECO:0000255|HAMAP-Rule:MF_01244};
DE            EC=1.4.1.- {ECO:0000255|HAMAP-Rule:MF_01244};
GN   OrderedLocusNames=PERMA_1476;
OS   Persephonella marina (strain DSM 14350 / EX-H1).
OC   Bacteria; Aquificae; Aquificales; Hydrogenothermaceae; Persephonella.
OX   NCBI_TaxID=123214;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14350 / EX-H1;
RX   PubMed=19136599; DOI=10.1128/jb.01645-08;
RA   Reysenbach A.-L., Hamamura N., Podar M., Griffiths E., Ferreira S.,
RA   Hochstein R., Heidelberg J., Johnson J., Mead D., Pohorille A.,
RA   Sarmiento M., Schweighofer K., Seshadri R., Voytek M.A.;
RT   "Complete and draft genome sequences of six members of the Aquificales.";
RL   J. Bacteriol. 191:1992-1993(2009).
CC   -!- SIMILARITY: Belongs to the archaeal-type DHQ synthase family.
CC       {ECO:0000255|HAMAP-Rule:MF_01244}.
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DR   EMBL; CP001230; ACO03774.1; -; Genomic_DNA.
DR   RefSeq; WP_012676013.1; NC_012440.1.
DR   AlphaFoldDB; C0QRE8; -.
DR   STRING; 123214.PERMA_1476; -.
DR   EnsemblBacteria; ACO03774; ACO03774; PERMA_1476.
DR   KEGG; pmx:PERMA_1476; -.
DR   eggNOG; COG1465; Bacteria.
DR   HOGENOM; CLU_056379_0_0_0; -.
DR   OMA; HFGMAIK; -.
DR   OrthoDB; 764330at2; -.
DR   Proteomes; UP000001366; Chromosome.
DR   GO; GO:0003856; F:3-dehydroquinate synthase activity; IEA:InterPro.
DR   GO; GO:0051287; F:NAD binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016639; F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor; IEA:UniProtKB-UniRule.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0008652; P:cellular amino acid biosynthetic process; IEA:UniProtKB-KW.
DR   HAMAP; MF_01244; Arch_DHQ_synthase; 1.
DR   InterPro; IPR002812; DHQ_synth.
DR   PANTHER; PTHR33563; PTHR33563; 1.
DR   Pfam; PF01959; DHQS; 1.
DR   PIRSF; PIRSF006655; DHQ_synth; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Aromatic amino acid biosynthesis; NAD;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..331
FT                   /note="3-dehydroquinate synthase homolog"
FT                   /id="PRO_1000165042"
SQ   SEQUENCE   331 AA;  36163 MW;  076CB164584E4881 CRC64;
     MKEFIVNAIN YDKKIVTTAI ESGADYIIIP EDKEEEAKKL GRVNFIIADK KGNLTDDFVI
     VTIKNKQDEE KAAQLAKAGK KVIVRTTDWT IIPLENLIAQ SENIYAEVKN ADEASIAVGI
     LEKGVKGVVL ETEDLNEIKR VASVIKETTE KVELIRAKVT AIIPVGMGDR VAVDTTSLFK
     RGEGMLVGNS SAGMILVHAE TEESPYVASR PFRVNAGAVH MYTRVPGGKT VYLCELEAGK
     EVMAYDIDGN GRAVVVGRAK IERRPMLLIE AEYNGKKLSA VLQNAETIRV VGGDGSLISV
     VDLKEGDEIL GYVEEAGRHF GMKVEETILE K