ID   DHSL_COXBU              Reviewed;         352 AA.
AC   P59650;
DT   30-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT   30-APR-2003, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=Deoxyhypusine synthase-like protein;
DE            EC=2.5.-.-;
GN   OrderedLocusNames=CBU_0721;
OS   Coxiella burnetii (strain RSA 493 / Nine Mile phase I).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales; Coxiellaceae;
OC   Coxiella.
OX   NCBI_TaxID=227377;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RSA 493 / Nine Mile phase I;
RX   PubMed=12704232; DOI=10.1073/pnas.0931379100;
RA   Seshadri R., Paulsen I.T., Eisen J.A., Read T.D., Nelson K.E., Nelson W.C.,
RA   Ward N.L., Tettelin H., Davidsen T.M., Beanan M.J., DeBoy R.T.,
RA   Daugherty S.C., Brinkac L.M., Madupu R., Dodson R.J., Khouri H.M.,
RA   Lee K.H., Carty H.A., Scanlan D., Heinzen R.A., Thompson H.A., Samuel J.E.,
RA   Fraser C.M., Heidelberg J.F.;
RT   "Complete genome sequence of the Q-fever pathogen, Coxiella burnetii.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:5455-5460(2003).
CC   -!- SIMILARITY: Belongs to the deoxyhypusine synthase family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAO90263.2; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE016828; AAO90263.2; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_819749.2; NC_002971.3.
DR   AlphaFoldDB; P59650; -.
DR   SMR; P59650; -.
DR   STRING; 227377.CBU_0721; -.
DR   EnsemblBacteria; AAO90263; AAO90263; CBU_0721.
DR   GeneID; 1208611; -.
DR   KEGG; cbu:CBU_0721; -.
DR   PATRIC; fig|227377.7.peg.706; -.
DR   eggNOG; COG1899; Bacteria.
DR   HOGENOM; CLU_039781_1_0_6; -.
DR   OMA; FWSYFCQ; -.
DR   Proteomes; UP000002671; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0034038; F:deoxyhypusine synthase activity; IBA:GO_Central.
DR   GO; GO:0008612; P:peptidyl-lysine modification to peptidyl-hypusine; IBA:GO_Central.
DR   Gene3D; 3.40.910.10; -; 1.
DR   HAMAP; MF_00640; DHS_like; 1.
DR   InterPro; IPR002773; Deoxyhypusine_synthase.
DR   InterPro; IPR023496; Deoxyhypusine_synthase-like.
DR   InterPro; IPR036982; Deoxyhypusine_synthase_sf.
DR   InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR   PANTHER; PTHR11703; PTHR11703; 1.
DR   Pfam; PF01916; DS; 1.
DR   SUPFAM; SSF52467; SSF52467; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Transferase.
FT   CHAIN           1..352
FT                   /note="Deoxyhypusine synthase-like protein"
FT                   /id="PRO_0000134515"
SQ   SEQUENCE   352 AA;  39570 MW;  023C4DC8EFA23406 CRC64;
     MKNKNLSMPS LKEKLLQETV EHIDITRFDA RPIIDAMDHM SFTSRDLARA TQIFNRMLQD
     EQCSIILSLA GSTSAGGCMK LYADLVKYNM VDAIVATGAS IVDMDFFEAL GFRHYQGSPA
     VEDRQLRDLY IDRIYDTYID EEDLQRCDHT IYEIANSLEP RPYSSREFIH HMGAYLAQGK
     AKKEESLVQL AYEHDVPIFC PAFTDSSAGF GLVLHQVKNP DRHLTIDSIR DFRELTDIKI
     KAGTTGLLMI GGGVPKNFVQ DTVVCAEVIG KTVDMHKYAI QITVADVRDG ACSSSTLKEA
     CSWGKVDTAY EQMVYAEATS GLPLLASDAY HRGYWKDRSP RQYANLFKSE SK