ID   DIAA_KLEP7              Reviewed;         196 AA.
AC   A6TEG8;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=DnaA initiator-associating protein DiaA {ECO:0000255|HAMAP-Rule:MF_01157};
GN   Name=diaA {ECO:0000255|HAMAP-Rule:MF_01157};
GN   OrderedLocusNames=KPN78578_35280; ORFNames=KPN_03557;
OS   Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=272620;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700721 / MGH 78578;
RG   The Klebsiella pneumonia Genome Sequencing Project;
RA   McClelland M., Sanderson E.K., Spieth J., Clifton W.S., Latreille P.,
RA   Sabo A., Pepin K., Bhonagiri V., Porwollik S., Ali J., Wilson R.K.;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for the timely initiation of chromosomal replication
CC       via direct interactions with the DnaA initiator protein.
CC       {ECO:0000255|HAMAP-Rule:MF_01157}.
CC   -!- SUBUNIT: Homotetramer; dimer of dimers. {ECO:0000255|HAMAP-
CC       Rule:MF_01157}.
CC   -!- SIMILARITY: Belongs to the SIS family. DiaA subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01157}.
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DR   EMBL; CP000647; ABR78952.1; -; Genomic_DNA.
DR   RefSeq; WP_002918211.1; NC_009648.1.
DR   AlphaFoldDB; A6TEG8; -.
DR   SMR; A6TEG8; -.
DR   STRING; 272620.KPN_03557; -.
DR   EnsemblBacteria; ABR78952; ABR78952; KPN_03557.
DR   GeneID; 64335524; -.
DR   GeneID; 66587606; -.
DR   KEGG; kpn:KPN_03557; -.
DR   HOGENOM; CLU_080999_3_1_6; -.
DR   OMA; DVHICVP; -.
DR   Proteomes; UP000000265; Chromosome.
DR   GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR   GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd05006; SIS_GmhA; 1.
DR   HAMAP; MF_01157; SIS_DiaA; 1.
DR   InterPro; IPR023070; DiaA.
DR   InterPro; IPR035461; GmhA/DiaA.
DR   InterPro; IPR001347; SIS_dom.
DR   InterPro; IPR046348; SIS_dom_sf.
DR   Pfam; PF13580; SIS_2; 1.
DR   SUPFAM; SSF53697; SSF53697; 1.
DR   PROSITE; PS51464; SIS; 1.
PE   3: Inferred from homology;
KW   DNA replication; Reference proteome.
FT   CHAIN           1..196
FT                   /note="DnaA initiator-associating protein DiaA"
FT                   /id="PRO_1000065545"
FT   DOMAIN          34..196
FT                   /note="SIS"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01157"
SQ   SEQUENCE   196 AA;  21092 MW;  812DBE5341D98853 CRC64;
     MLDRIKACFT ESIQTQIAAA EALPDAISRA AMTLVQSLLN GNKILCCGNG TSAANAQHFA
     ASMINRFETE RPGLPAIALN TDNVVLTAIA NDRLHDEIYA KQVRALGHAG DVLLAISTRG
     NSRDIVKAVE AAVTRDMTIV ALTGYDGGEL AGLLGQQDVE IRIPSHRSAR IQEMHMLTVN
     CLCDLIDNTL FPHQDD