ID   DIAA_PECAS              Reviewed;         196 AA.
AC   Q6DAD4;
DT   04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=DnaA initiator-associating protein DiaA {ECO:0000255|HAMAP-Rule:MF_01157};
GN   Name=diaA {ECO:0000255|HAMAP-Rule:MF_01157}; OrderedLocusNames=ECA0320;
OS   Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia
OS   carotovora subsp. atroseptica).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Pectobacteriaceae; Pectobacterium.
OX   NCBI_TaxID=218491;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SCRI 1043 / ATCC BAA-672;
RX   PubMed=15263089; DOI=10.1073/pnas.0402424101;
RA   Bell K.S., Sebaihia M., Pritchard L., Holden M.T.G., Hyman L.J.,
RA   Holeva M.C., Thomson N.R., Bentley S.D., Churcher L.J.C., Mungall K.,
RA   Atkin R., Bason N., Brooks K., Chillingworth T., Clark K., Doggett J.,
RA   Fraser A., Hance Z., Hauser H., Jagels K., Moule S., Norbertczak H.,
RA   Ormond D., Price C., Quail M.A., Sanders M., Walker D., Whitehead S.,
RA   Salmond G.P.C., Birch P.R.J., Parkhill J., Toth I.K.;
RT   "Genome sequence of the enterobacterial phytopathogen Erwinia carotovora
RT   subsp. atroseptica and characterization of virulence factors.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:11105-11110(2004).
CC   -!- FUNCTION: Required for the timely initiation of chromosomal replication
CC       via direct interactions with the DnaA initiator protein.
CC       {ECO:0000255|HAMAP-Rule:MF_01157}.
CC   -!- SUBUNIT: Homotetramer; dimer of dimers. {ECO:0000255|HAMAP-
CC       Rule:MF_01157}.
CC   -!- SIMILARITY: Belongs to the SIS family. DiaA subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01157}.
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DR   EMBL; BX950851; CAG73240.1; -; Genomic_DNA.
DR   RefSeq; WP_011091952.1; NC_004547.2.
DR   AlphaFoldDB; Q6DAD4; -.
DR   SMR; Q6DAD4; -.
DR   STRING; 218491.ECA0320; -.
DR   EnsemblBacteria; CAG73240; CAG73240; ECA0320.
DR   GeneID; 61410617; -.
DR   GeneID; 66800600; -.
DR   KEGG; eca:ECA0320; -.
DR   eggNOG; COG0279; Bacteria.
DR   HOGENOM; CLU_080999_3_1_6; -.
DR   OMA; DVHICVP; -.
DR   OrthoDB; 1571626at2; -.
DR   Proteomes; UP000007966; Chromosome.
DR   GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR   GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd05006; SIS_GmhA; 1.
DR   HAMAP; MF_01157; SIS_DiaA; 1.
DR   InterPro; IPR023070; DiaA.
DR   InterPro; IPR035461; GmhA/DiaA.
DR   InterPro; IPR001347; SIS_dom.
DR   InterPro; IPR046348; SIS_dom_sf.
DR   Pfam; PF13580; SIS_2; 1.
DR   SUPFAM; SSF53697; SSF53697; 1.
DR   PROSITE; PS51464; SIS; 1.
PE   3: Inferred from homology;
KW   DNA replication; Reference proteome.
FT   CHAIN           1..196
FT                   /note="DnaA initiator-associating protein DiaA"
FT                   /id="PRO_0000136558"
FT   DOMAIN          34..196
FT                   /note="SIS"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01157"
SQ   SEQUENCE   196 AA;  21051 MW;  6381FF6DA5FA7813 CRC64;
     MLDRIKVCFT ESIQTQIAAA EALPDAISRG AIAMVQSLLN GNKILCCGNG TSAANSQHFA
     ASMINRFEAE RPSLPAIALN ADNVVLTAIA NDRLHEEIYA KQVRALGQAG DVLLAISTRG
     NSRDIVKAVE SAVTRDMTIV ALTGYDGGEL AGLLGPQDVE IRIPSHRSAR IQEMHMLTVN
     CLCDLIDNTL FPHQND