DIAA_SALPC
ID DIAA_SALPC Reviewed; 196 AA.
AC C0PZ34;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-MAY-2009, sequence version 1.
DT 25-MAY-2022, entry version 60.
DE RecName: Full=DnaA initiator-associating protein DiaA {ECO:0000255|HAMAP-Rule:MF_01157};
GN Name=diaA {ECO:0000255|HAMAP-Rule:MF_01157}; OrderedLocusNames=SPC_3337;
OS Salmonella paratyphi C (strain RKS4594).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=476213;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RKS4594;
RX PubMed=19229335; DOI=10.1371/journal.pone.0004510;
RA Liu W.-Q., Feng Y., Wang Y., Zou Q.-H., Chen F., Guo J.-T., Peng Y.-H.,
RA Jin Y., Li Y.-G., Hu S.-N., Johnston R.N., Liu G.-R., Liu S.-L.;
RT "Salmonella paratyphi C: genetic divergence from Salmonella choleraesuis
RT and pathogenic convergence with Salmonella typhi.";
RL PLoS ONE 4:E4510-E4510(2009).
CC -!- FUNCTION: Required for the timely initiation of chromosomal replication
CC via direct interactions with the DnaA initiator protein.
CC {ECO:0000255|HAMAP-Rule:MF_01157}.
CC -!- SUBUNIT: Homotetramer; dimer of dimers. {ECO:0000255|HAMAP-
CC Rule:MF_01157}.
CC -!- SIMILARITY: Belongs to the SIS family. DiaA subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_01157}.
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DR EMBL; CP000857; ACN47422.1; -; Genomic_DNA.
DR RefSeq; WP_000893481.1; NC_012125.1.
DR AlphaFoldDB; C0PZ34; -.
DR SMR; C0PZ34; -.
DR EnsemblBacteria; ACN47422; ACN47422; SPC_3337.
DR GeneID; 66757607; -.
DR KEGG; sei:SPC_3337; -.
DR HOGENOM; CLU_080999_3_1_6; -.
DR OMA; DVHICVP; -.
DR Proteomes; UP000001599; Chromosome.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR CDD; cd05006; SIS_GmhA; 1.
DR HAMAP; MF_01157; SIS_DiaA; 1.
DR InterPro; IPR023070; DiaA.
DR InterPro; IPR035461; GmhA/DiaA.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR Pfam; PF13580; SIS_2; 1.
DR SUPFAM; SSF53697; SSF53697; 1.
DR PROSITE; PS51464; SIS; 1.
PE 3: Inferred from homology;
KW DNA replication.
FT CHAIN 1..196
FT /note="DnaA initiator-associating protein DiaA"
FT /id="PRO_1000164296"
FT DOMAIN 34..196
FT /note="SIS"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01157"
SQ SEQUENCE 196 AA; 21109 MW; 3D5116DB8D03F790 CRC64;
MLERIKVCFT ESIQTQIAAA EALPDAISRA AMTLVHSLLN GNKILCCGNG TSAANAQHFA
ASMINRFETE RPSLPAIALN TDNVVLTAIA NDRLHDEVYA KQVRALGHAG DVLLAISTRG
NSRDIVKAVE AAVTRDMTIV ALTGYDGGEL AGLLGPQDVE IRIPSHHSAR IQEMHMLTVN
CLCDLIDNTL FPHQDD