ID   DIAA_SALTY              Reviewed;         196 AA.
AC   Q8ZLU2;
DT   04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=DnaA initiator-associating protein DiaA {ECO:0000255|HAMAP-Rule:MF_01157};
GN   Name=diaA {ECO:0000255|HAMAP-Rule:MF_01157}; OrderedLocusNames=STM3266;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Required for the timely initiation of chromosomal replication
CC       via direct interactions with the DnaA initiator protein.
CC       {ECO:0000255|HAMAP-Rule:MF_01157}.
CC   -!- SUBUNIT: Homotetramer; dimer of dimers. {ECO:0000255|HAMAP-
CC       Rule:MF_01157}.
CC   -!- SIMILARITY: Belongs to the SIS family. DiaA subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01157}.
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DR   EMBL; AE006468; AAL22138.1; -; Genomic_DNA.
DR   RefSeq; NP_462179.1; NC_003197.2.
DR   RefSeq; WP_000893481.1; NC_003197.2.
DR   AlphaFoldDB; Q8ZLU2; -.
DR   SMR; Q8ZLU2; -.
DR   STRING; 99287.STM3266; -.
DR   PaxDb; Q8ZLU2; -.
DR   EnsemblBacteria; AAL22138; AAL22138; STM3266.
DR   GeneID; 1254789; -.
DR   GeneID; 66757607; -.
DR   KEGG; stm:STM3266; -.
DR   PATRIC; fig|99287.12.peg.3465; -.
DR   HOGENOM; CLU_080999_3_1_6; -.
DR   OMA; DVHICVP; -.
DR   PhylomeDB; Q8ZLU2; -.
DR   BioCyc; SENT99287:STM3266-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR   GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd05006; SIS_GmhA; 1.
DR   HAMAP; MF_01157; SIS_DiaA; 1.
DR   InterPro; IPR023070; DiaA.
DR   InterPro; IPR035461; GmhA/DiaA.
DR   InterPro; IPR001347; SIS_dom.
DR   InterPro; IPR046348; SIS_dom_sf.
DR   Pfam; PF13580; SIS_2; 1.
DR   SUPFAM; SSF53697; SSF53697; 1.
DR   PROSITE; PS51464; SIS; 1.
PE   3: Inferred from homology;
KW   DNA replication; Reference proteome.
FT   CHAIN           1..196
FT                   /note="DnaA initiator-associating protein DiaA"
FT                   /id="PRO_0000136561"
FT   DOMAIN          34..196
FT                   /note="SIS"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01157"
SQ   SEQUENCE   196 AA;  21109 MW;  3D5116DB8D03F790 CRC64;
     MLERIKVCFT ESIQTQIAAA EALPDAISRA AMTLVHSLLN GNKILCCGNG TSAANAQHFA
     ASMINRFETE RPSLPAIALN TDNVVLTAIA NDRLHDEVYA KQVRALGHAG DVLLAISTRG
     NSRDIVKAVE AAVTRDMTIV ALTGYDGGEL AGLLGPQDVE IRIPSHHSAR IQEMHMLTVN
     CLCDLIDNTL FPHQDD