ID   DIAA_YERE8              Reviewed;         196 AA.
AC   A1JR74;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=DnaA initiator-associating protein DiaA {ECO:0000255|HAMAP-Rule:MF_01157};
GN   Name=diaA {ECO:0000255|HAMAP-Rule:MF_01157}; OrderedLocusNames=YE3729;
OS   Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 /
OS   8081).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=393305;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 13174 / 8081;
RX   PubMed=17173484; DOI=10.1371/journal.pgen.0020206;
RA   Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L.,
RA   Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T.,
RA   Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S.,
RA   Sanders M., Whitehead S., Quail M.A., Dougan G., Parkhill J.,
RA   Prentice M.B.;
RT   "The complete genome sequence and comparative genome analysis of the high
RT   pathogenicity Yersinia enterocolitica strain 8081.";
RL   PLoS Genet. 2:2039-2051(2006).
CC   -!- FUNCTION: Required for the timely initiation of chromosomal replication
CC       via direct interactions with the DnaA initiator protein.
CC       {ECO:0000255|HAMAP-Rule:MF_01157}.
CC   -!- SUBUNIT: Homotetramer; dimer of dimers. {ECO:0000255|HAMAP-
CC       Rule:MF_01157}.
CC   -!- SIMILARITY: Belongs to the SIS family. DiaA subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01157}.
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DR   EMBL; AM286415; CAL13755.1; -; Genomic_DNA.
DR   RefSeq; WP_004710884.1; NC_008800.1.
DR   RefSeq; YP_001007883.1; NC_008800.1.
DR   AlphaFoldDB; A1JR74; -.
DR   SMR; A1JR74; -.
DR   STRING; 393305.YE3729; -.
DR   EnsemblBacteria; CAL13755; CAL13755; YE3729.
DR   GeneID; 67420376; -.
DR   KEGG; yen:YE3729; -.
DR   PATRIC; fig|393305.7.peg.3971; -.
DR   eggNOG; COG0279; Bacteria.
DR   HOGENOM; CLU_080999_3_1_6; -.
DR   OMA; DVHICVP; -.
DR   Proteomes; UP000000642; Chromosome.
DR   GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR   GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd05006; SIS_GmhA; 1.
DR   HAMAP; MF_01157; SIS_DiaA; 1.
DR   InterPro; IPR023070; DiaA.
DR   InterPro; IPR035461; GmhA/DiaA.
DR   InterPro; IPR001347; SIS_dom.
DR   InterPro; IPR046348; SIS_dom_sf.
DR   Pfam; PF13580; SIS_2; 1.
DR   SUPFAM; SSF53697; SSF53697; 1.
DR   PROSITE; PS51464; SIS; 1.
PE   3: Inferred from homology;
KW   DNA replication.
FT   CHAIN           1..196
FT                   /note="DnaA initiator-associating protein DiaA"
FT                   /id="PRO_1000065553"
FT   DOMAIN          34..196
FT                   /note="SIS"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01157"
SQ   SEQUENCE   196 AA;  21032 MW;  C834A7B1AD661408 CRC64;
     MLDRIKGCFT ESIQTQIAAA EALPDAISRA AMTLVQSLLN GNKILCCGNG TSAANAQHFA
     ASMINRFETE RPSLPAIALN ADNVVLTAIA NDRLHDEVYA KQVRALGHAG DVLLAISTRG
     NSRDIVKAVE AAVTRDMTIV ALTGYDGGEL AGLLGQQDVE IRIPSHRSAR VQELHMLTVN
     CLCDLIDNTL FPHQDD