DIAA_YERPE
ID DIAA_YERPE Reviewed; 196 AA.
AC Q8ZB74; Q0WBA1; Q74PT2; Q7CLA1;
DT 04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 25-MAY-2022, entry version 106.
DE RecName: Full=DnaA initiator-associating protein DiaA {ECO:0000255|HAMAP-Rule:MF_01157};
GN Name=diaA {ECO:0000255|HAMAP-Rule:MF_01157};
GN OrderedLocusNames=YPO3550, y0122, YP_3804;
OS Yersinia pestis.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIM10+ / Biovar Mediaevalis;
RX PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT "Genome sequence of Yersinia pestis KIM.";
RL J. Bacteriol. 184:4601-4611(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- FUNCTION: Required for the timely initiation of chromosomal replication
CC via direct interactions with the DnaA initiator protein.
CC {ECO:0000255|HAMAP-Rule:MF_01157}.
CC -!- SUBUNIT: Homotetramer; dimer of dimers. {ECO:0000255|HAMAP-
CC Rule:MF_01157}.
CC -!- SIMILARITY: Belongs to the SIS family. DiaA subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_01157}.
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DR EMBL; AL590842; CAL22138.1; -; Genomic_DNA.
DR EMBL; AE009952; AAM83716.1; -; Genomic_DNA.
DR EMBL; AE017042; AAS63951.1; -; Genomic_DNA.
DR PIR; AG0431; AG0431.
DR RefSeq; WP_002210146.1; NZ_WHLN01000066.1.
DR RefSeq; YP_002348437.1; NC_003143.1.
DR AlphaFoldDB; Q8ZB74; -.
DR SMR; Q8ZB74; -.
DR STRING; 214092.YPO3550; -.
DR PaxDb; Q8ZB74; -.
DR DNASU; 1145069; -.
DR EnsemblBacteria; AAM83716; AAM83716; y0122.
DR EnsemblBacteria; AAS63951; AAS63951; YP_3804.
DR GeneID; 57975165; -.
DR KEGG; ype:YPO3550; -.
DR KEGG; ypk:y0122; -.
DR KEGG; ypm:YP_3804; -.
DR PATRIC; fig|214092.21.peg.4044; -.
DR eggNOG; COG0279; Bacteria.
DR HOGENOM; CLU_080999_3_1_6; -.
DR OMA; DVHICVP; -.
DR Proteomes; UP000000815; Chromosome.
DR Proteomes; UP000001019; Chromosome.
DR Proteomes; UP000002490; Chromosome.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR CDD; cd05006; SIS_GmhA; 1.
DR HAMAP; MF_01157; SIS_DiaA; 1.
DR InterPro; IPR023070; DiaA.
DR InterPro; IPR035461; GmhA/DiaA.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR Pfam; PF13580; SIS_2; 1.
DR SUPFAM; SSF53697; SSF53697; 1.
DR PROSITE; PS51464; SIS; 1.
PE 3: Inferred from homology;
KW DNA replication; Reference proteome.
FT CHAIN 1..196
FT /note="DnaA initiator-associating protein DiaA"
FT /id="PRO_0000136563"
FT DOMAIN 34..196
FT /note="SIS"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01157"
SQ SEQUENCE 196 AA; 20938 MW; 157818E927A8AF68 CRC64;
MLERIKGCFT ESIQTQIAAA EALPDAISCA AMALVQSLLN GNKILCCGNG TSAANAQHFA
ASMINRFETE RPSLPAIALN ADNVVLTAIT NDRLHDEVYA KQVRALGQAG DVLLAISTRG
NSRDIVKAVE AAVTRDMTIV ALTGYDGGEL AGLLGQLDVE IRIPSHRGAR VQELHMLTVN
CLCDLIDNTL FPHQND