DIAA_YERPP
ID DIAA_YERPP Reviewed; 196 AA.
AC A4THK2;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 1.
DT 25-MAY-2022, entry version 73.
DE RecName: Full=DnaA initiator-associating protein DiaA {ECO:0000255|HAMAP-Rule:MF_01157};
GN Name=diaA {ECO:0000255|HAMAP-Rule:MF_01157}; OrderedLocusNames=YPDSF_0347;
OS Yersinia pestis (strain Pestoides F).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=386656;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pestoides F;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Di Bartolo G., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA Larimer F., Land M., Hauser L., Worsham P., Chu M., Bearden S., Garcia E.,
RA Richardson P.;
RT "Complete sequence of chromosome of Yersinia pestis Pestoides F.";
RL Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the timely initiation of chromosomal replication
CC via direct interactions with the DnaA initiator protein.
CC {ECO:0000255|HAMAP-Rule:MF_01157}.
CC -!- SUBUNIT: Homotetramer; dimer of dimers. {ECO:0000255|HAMAP-
CC Rule:MF_01157}.
CC -!- SIMILARITY: Belongs to the SIS family. DiaA subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_01157}.
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DR EMBL; CP000668; ABP38764.1; -; Genomic_DNA.
DR RefSeq; WP_002210146.1; NZ_CP009715.1.
DR AlphaFoldDB; A4THK2; -.
DR SMR; A4THK2; -.
DR GeneID; 57975165; -.
DR KEGG; ypp:YPDSF_0347; -.
DR PATRIC; fig|386656.14.peg.1648; -.
DR OMA; DVHICVP; -.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR CDD; cd05006; SIS_GmhA; 1.
DR HAMAP; MF_01157; SIS_DiaA; 1.
DR InterPro; IPR023070; DiaA.
DR InterPro; IPR035461; GmhA/DiaA.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR Pfam; PF13580; SIS_2; 1.
DR SUPFAM; SSF53697; SSF53697; 1.
DR PROSITE; PS51464; SIS; 1.
PE 3: Inferred from homology;
KW DNA replication.
FT CHAIN 1..196
FT /note="DnaA initiator-associating protein DiaA"
FT /id="PRO_1000065557"
FT DOMAIN 34..196
FT /note="SIS"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01157"
SQ SEQUENCE 196 AA; 20938 MW; 157818E927A8AF68 CRC64;
MLERIKGCFT ESIQTQIAAA EALPDAISCA AMALVQSLLN GNKILCCGNG TSAANAQHFA
ASMINRFETE RPSLPAIALN ADNVVLTAIT NDRLHDEVYA KQVRALGQAG DVLLAISTRG
NSRDIVKAVE AAVTRDMTIV ALTGYDGGEL AGLLGQLDVE IRIPSHRGAR VQELHMLTVN
CLCDLIDNTL FPHQND